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What is the general anatomy of the human prostate?

The human prostate can generally be described as being glandular epithelium (parenchymal) surrounded by a fibromuscular stroma. The parenchymal portion of the prostate, or of any organ in the body, is epithelial like in nature and contains the...

Can Lonzas PrEC cells be co-cultured with Lonzas PrSC cells?

While Lonza has never attempted to co-culture Prostate Epithelial Cells (PrEC) and Prostate Stromal Cells (PrSC) together in-house, the recommendation of Lonza Research & Development would be to plate and culture the PrEC and PrSC cells together in...

Where are Lonzas PrSC cells isolated from? What cells will be in the PrSC population?

Lonza’s Prostate Stromal Cells (PrSC) are isolated from the stroma of the prostate. Lonza’s Prostate Stromal Cells (PrSC) are a mixed population of cells, however, the majority of the cells in this population are fibroblastic in origin. It is not...

Where are Lonzas PrEC cells isolated from?

Lonza obtains our Lonza’s Prostate Epithelial Cells (PrEC) from the glandular epithelium (parenchymal portion) of the prostate which spans the entire prostate and not from one specific region.

Do the LGM-3 (catalog no. CC-3211) and HPGM (catalog no. PT-3926) media contain antibiotics?

Both the LGM-3 (catalog no. CC-3211) and HPGM (catalog no. PT-3926) media contain Gentamicin Sulfate at a final concentration of 50 mg/L.

Where are Lonzas PrSMC cells isolated from?

Lonza’s Prostate Smooth Muscle Cells (PrSMC) are isolated from the stroma and the vasculature of the prostate. Unfortunately, there is no way to distinguish between smooth muscle cells from the stroma and smooth muscle cells from the vasculature and...

Do the LGM-3 (catalog no. CC-3211) and HPGM (catalog no. PT-3926) media contain proteins?

Both the LGM-3 (catalog no. CC-3211) and HPGM (catalog no. PT-3926) media contain Human Recombinant Insulin, Human Albumin, and Human Transferrin.

How long can Lonzas normal human astrocytes survive without fetal bovine serum (FBS)?

Lonza recommends culturing normal human astrocytes (NHA) in Lonza’s AGM™ Astrocyte Growth Medium which contains fetal bovine serum (FBS) at a final concentration of 3.0%. For some applications, researchers may need to serum starve their cells. Under...

Do the LGM-3 (catalog no. CC-3211) and HPGM (catalog no. PT-3926) media contain phenol red?

Both the LGM-3 (catalog no. CC-3211) and HPGM (catalog no. PT-3926) media contain phenol red. Lonza does not currently offer a phenol red free version or alternative to either of these products as a standard product.

Are Lonzas normal human astrocytes Type I or Type II in origin?

Type I astrocytes are protoplasmic and isolated from gray matter, whereas Type II astrocytes are fibrous and isolated from white matter. As Lonza’s normal human astrocytes (NHA) are primarily isolated from the cerebral cortex (or forebrain from...
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