Search Results

Resveratrol and estradiol rapidly activate MAPK signaling through estrogen receptors alpha and beta in endothelial cells

...HUVEC), and human microvascular EC (HMEC). We report that BAEC, HUVEC, and HMEC express ERalpha and ERbeta. We demonstrate that resveratrol and estradiol (E2) rapidly activated MAPK in a MEK-1, Src, matrix metalloproteinase (MMP), and epidermal growth...

Authors: Klinge CM, Blankenship KA, Risinger KE, Bhatnagar S, Noisin EL, Sumanasekera WK, Brey DM and Keynton...

SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence

...depletion by RNA interference in human umbilical vein endothelial cells (HUVEC) and aortic endothelial cells reduced cell proliferation, increased the fraction of senescence-associated-ß-galactosidase-positive cells, and diminished the ability of the cells...

Authors: Cardus A, Uryga AK, Walters G, Erusalimsky JD.

Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell

...been used for prevention of illness in Korea. In this study, we investigated the mechanism(s) by which ginsenoside Rg2 may inhibit VCAM-1 and ICAM-1 expressions stimulated with lipopolysaccharide (LPS) in human umbilical vein endothelial cell (HUVEC...

Authors: Cho YS, Kim CH, Ha TS, Lee SJ, Ahn HY

Progesterone withdrawal causes endothelin release from cultured human uterine microvascular endothelial cells

...induces an upregulation of the thrombin receptor in the small uterine arteries leading to an increased thrombin response and subsequent endothelin release. METHODS: Endothelial cells from human umbilical cord (HUVECs) and from human small uterine...

Authors: Edlund M, Andersson E, Fried G.

Critical role of the a1-Na+, K +-ATPase subunit in insensitivity of rodent cells to cytotoxic action of ouabain.

...cells (HUVEC and RAEC), and human and rat brain astrocytes. 6-h exposure of HASMC and HUVEC to 3 µM ouabain dramatically increased the intracellular [Na+]/[K+] ratio to the same extend as in RASMC and RAEC treated with 3000 µM ouabain. In 24, 3 µM...

Authors: Akimova OA, Tverskoi AM, Smolyaninova LV, Mongin AA, Lopina OD, La J, Dulin NO, Orlov SN

SST Peer Reviewed

Prevascularization of 3D printed bone scaffolds by bioactive hydrogels and cell co-culture

...prevascularization strategy to generate prevascularized bone constructs. Human adipose derived mesenchymal stem cells (ADMSC) and human umbilical vein endothelial cells (HUVEC) were encapsulated within our bioactive hydrogels, and the effects of culture conditions...

Authors: Kuss MA1,2, Wu S1,2, Wang Y1,2, Untrauer JB3, Li W4, Lim JY1,4, Duan B1,2,5.

Acidosis activation of the proton-sensing GPR4 receptor stimulates vascular endothelial cell inflammatory responses revealed by transcriptome analysis.

...response in primary human umbilical vein endothelial cells (HUVEC) with varying level of GPR4. The results demonstrated that acidosis activation of GPR4 in HUVEC substantially increased the expression of a number of inflammatory genes such as chemokines...

Authors: Dong L, Li Z, Leffler NR, Asch AS, Chi JT, Yang LV.

SST Peer Reviewed

Pleiotrophin induces nitric oxide dependent migration of endothelial progenitor cells

...umbilical vein endothelial cells (HUVECs), but not of human coronary artery smooth muscle cells (CASMCs) and T98G glioblastoma cells that lack PTN receptors. The degree of chemotaxis was comparable to that induced by the angiogenic factors VEGF...

Authors: Heiss C, Wong ML, Block VI, Lao D, Real WM, Yeghiazarians Y, Lee RJ, Springer ML

Cathepsin L derived from skeletal muscle cells transfected with bFGF promotes endothelial cell migration

...and LacZ-CM, from SkMCs infected by Ad/bFGF or Ad/LacZ, respectively. Cell migration significantly increased in HUVECs incubated with bFGF-CM compared to cells incubated with LacZ-CM. Interestingly, HUVEC migration in response to bFGF-CM was only partially...

Authors: Chung JH, Im EK, Jin TW, Lee SM, Kim SH, Choi EY, Shin MJ, Lee KH, Jang Y

Attenuation of hind-limb ischemia in mice with endothelial-like cells derived from different sources of human stem cells.

...HUVEC) and BM-EC (P>0.05). While increased expression of major angiogenic factors including epidermal growth factor, hepatocyte growth factor, vascular endothelial growth factor, placental growth factor and stromal derived factor-1 were observed in all...

Authors: Lai WH, Ho JC, Chan YC, Ng JH, Au KW, Wong LY, Siu CW, Tse HF.

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