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What is the typical cell distribution for peripheral blood mononuclear cells (PBMC) catalog number CC-2702? 

We don't characterize each lot of these cells. Therefore, we don't make any guarantee regarding cell type distribution.Typically, you would expect to see approximately 60-80% T Cells, 10-20% monocytes, and the remaining cells would be...

Can I store my cryopreserved primary cell ampule at 80°C?

No, cryopreserved cells should be stored in liquid or vapor phase nitrogen. Storing the cells at higher temperatures can irreversibly damage the cells.

Which mobilization regime has been used for the CD34+ cells from mobilized peripheral blood (4Y-101)? Can I also have the cells from donors treated with another mobilization regime?

The mobilized peripheral blood used for 4Y-101 is derived  from peripheral blood mobilized with Neupogen® 10 mcg/kg/day x 5 days. The cryopreserved cells can be isolated from day 5 and/or day 6 collections. It is possible to request...

How do you calculate a population doubling?

A population doubling is the total number of population doublings of a cell type since its initiation in vitro. The number of population doubling is calculated using the following equations:Cell count at day of passage /Cell count 24 hours after...

How do you calculate doubling time of a cell culture?

The doubling time is the number of hours it takes for a cell population to double in number. Doubling time is calculated using the following equation:Number of hours from 24 hours after seeding until passage/Population Doublings = Doubling Time...

Can serum be used with Lonza's SAECs?

No. Serum will induce squamous differentiation of primary airway epithelial cells. Our SAGM™ Small Airway Epithelial Cell Growth Medium BulletKit CC-3118 does not contain FBS or any other serum.

Are ciliated cells present in the SAECs?

There are usually ciliated cells present in the SAEC isolations, which shows that the tissue is good and healthy and that everything went well in the isolation process.  However, the cilia do not persist during submers culture and are...

Can I download the software for the FlashGel Camera from your website?  

Please check the serial number of your camera:For cameras shipped after September 2023 (serial # >3656), version 3.4.2 of the software is available for download here: https://lonza.picturepark.com/Go/1eIWBrJS/D/39003/1Compatible with Windows® XP...

Does DMSO (ex. brought in with the substrate) affect Nucleofection®?

Most research paper agrees that the upper limit of cell tolerance to DMSO presence in their cell culture media is about 1% final DMSO (this might vary with the cells and media).In the case of the Nucleofection®, the DMSO will likely be transfected...

What is the Cocoon® Technology? 

The Cocoon® Platform utilizes a single use, disposable cassette to functionally close and automate cell manufacturing. Primarily developed to automated all steps in CAR-T cell manufacturing, the Cocoon® Platform is being used for numerous...
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