Epithelial, bronchial (NHBE), human

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Human bronchial/tracheal epithelial cells isolated from the epithelial cells that line the airway above the bifurcation of the lungs.

Cell Type:
Respiratory Tract Epith.
Tissue Origin:
lung
Species:
human
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Research Area:
Cancer Research/Cell Biology
Cell Characteristics:
Adherent

Recommended Media

Bronchial Epithelial Cell Growth Medium

Airway cell media are serum-free media that have been optimized for the proliferation of airway cells.

BEGM is optimized to provide the best growth for Normal Human Bronchial/Tracheal Epithelial Cells.

B-ALI™ Bronchial Air Liquid Interface Media

Media developed specifically for cultivation of bronchial epithelial cells in an air-liquid interface system.

The B-ALI™ BulletKit includes:
 - B-ALI™ Growth Basal Medium (200 ml)
 - B-ALI™ Differentiation Basal Medium (500 ml)
 - B-ALI™ SingleQuots Kit

Transfection Information

Lonza Optimized Protocol
Optimization Guideline
Filter:
The table below shows data for the cell type and Nucleofector™ Platform selected. Those data are either based on Lonza Optimized Protocols or on results shared from customers who performed an optimization based on our guidelines. In case no data are shown for the selected Nucleofector™ Platform, please take a look at our optimization strategy to get further guidance on how to easily determine optimal Nucleofection conditions yourself.
Protocol Kit Program Cells Efficiency Viable Cells Substrate Format Platform
P3 96-DC-100 8e4 51-57% 50-56% Plasmid (general) 0.4 µg 20 µl 96-well
Epithelial, basic

W-001

 5e5 44-60% 33-69% Plasmid (general) 2 µg 100 µl I/II/2b
P3

DC-100

 8e4 51-57% 50-56% Plasmid (general) 0.4 µg 20 µl 4D X-Unit

Citations (150)

Imbalanced host response to SARS-CoV-2 drives development of COVID-19
Categories:
Primary Cells and Media 
Authors:
Daniel Blanco-Melo, Benjamin E. Nilsson-Payant, Wen-Chun Liu, Skyler Uhl, Daisy Hoagland, Rasmus Møller, Tristan X. Jordan, Kohei Oishi, Maryline Panis, David Sachs, Taia T. Wang, Robert E. Schwartz, Jean K. Lim, Randy A. Albrecht, BenjaminR. tenOever 
In:
Cell (2020) 182: 1-20 
SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems
Categories:
Primary Cells and Media 
Authors:
Daniel Blanco-Melo, Benjamin E. Nilsson-Payant, Wen-Chun Liu, Rasmus Møller, Maryline Panis, David Sachs, Randy A. Albrecht, Benjamin R. tenOever 
In:
BioResearch Open Access (2020) :  
Highly efficient genome editing in primary bronchial epithelial cells establishes FOXJ1 as essential for ciliation in human airways
Categories:
Primary Cells and Media, 3D Cell Culture , Transfection 
Authors:
Radu Rapiteanu??1, Tina Karagyozova1, Natalie Zimmermann2, Gareth Wayne1, MatteoMartufi1, Nikolai N Belyaev2, Kuljit Singh1, Joanna Betts1, Soren Beinke2 and Klio Maratou1 
In:
BioResearch Open Access (2019) 01: 01 
Optimization of Normal Human Bronchial Epithelial (NHBE) Cell 3D Cultures for in vitro Lung Model Studies.
Categories:
Primary Cells and Media 
Authors:
Rayner RE, Makena P, Prasad GL, Cormet-Boyaka E. 
In:
Scientific Reports (2019) 9(1): 500 
IL-13 regulates IL-17C expression by suppressing NF-?B-mediated transcriptional activation in airway epithelial cells.
Categories:
Primary Cells and Media 
Authors:
Yamanaka K1, Fujisawa T2, Kusagaya H3, Mori K3, Niwa M3, Furuhashi K4, Kono M4, Hamada E1, Suda T3, Maekawa M1 
In:
Biochem Biophys Res Commun (2017) 495: 1534-1540 
Fast-track development of an in vitro 3D lung/immune cell model to study Aspergillus infections.
Categories:
Primary Cells and Media 
Authors:
Chandorkar P, Posch W, Zaderer V, Blatzer M, Steger M, Ammann CG, Binder U, Hermann M, Hörtnagl P, Lass-Flörl C, Wilflingseder D. 
In:
Scientific Reports (2017) 7(1): 11644 
Fast-track development of an in vitro 3D lung/immune cell model to study Aspergillus infections.
Categories:
Primary Cells and Media, 3D Cell Culture  
Authors:
Chandorkar P, Posch W, Zaderer V, Blatzer M, Steger M, Ammann CG, Binder U, Hermann M, Hörtnagl P, Lass-Flörl C, Wilflingseder D 
In:
Scientific Reports (2017) 7(1): 10.1038/s41598-017-11271-4 
In vivo therapeutic efficacy of frog skin-derived peptides against Pseudomonas aeruginosa-induced pulmonary infection.
Categories:
Primary Cells and Media 
Authors:
Chen C, Mangoni ML, Di YP 
In:
Scientific Reports (2017) 7(1): doi: 10.1038/s41598-017-08361-8. 
In Vitro Experimental Model for the Long-Term Analysis of Cellular Dynamics During Bronchial Tree Development from Lung Epithelial Cells.
Categories:
Primary Cells and Media 
Authors:
Hagiwara M1, Maruta N2,3, Marumoto M2 
In:
Tissue Eng (2017) 23: 323-332 
Glucocorticoid Insensitivity in Virally Infected Airway Epithelial Cells Is Dependent on Transforming Growth Factor-ß Activity.
Categories:
Primary Cells and Media 
Authors:
Xia YC, Radwan A, Keenan CR, Langenbach SY, Li M, Radojicic D, Londrigan SL, Gualano RC, Stewart AG 
In:
PLoS Pathog (2017) 13(1): doi: 10.1371/journal.ppat.1006138 
Entry, Intracellular Survival, and Multinucleated-Giant-Cell-Forming Activity of Burkholderia pseudomallei in Human Primary Phagocytic and Nonphagocytic Cells.
Categories:
Primary Cells and Media 
Authors:
Whiteley L1, Meffert T1, Haug M1, Weidenmaier C1, Hopf V2, Bitschar K3, Schittek B3, Kohler C2, Steinmetz I2, West TE4, Schwarz S5 
In:
Infect Immun (2017) 85: e00468-17 
Activation of heat shock response augments fibroblast growth factor-1 expression in wounded lung epithelium.
Categories:
Primary Cells and Media 
Authors:
Scheraga RG, Thompson C, Tulapurkar ME, Nagarsekar AC, Cowan M, Potla R, Sun J, Cai R, Logun C, Shelhamer J, Todd NW, Singh IS, Luzina IG, Atamas SP, Hasday JD 
In:
Am J Physiol Lung Cell Mol Physiol (2016) 311(5): L941-L955 
I?B? Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae.
Categories:
Primary Cells and Media 
Authors:
Sundaram K, Rahman MA, Mitra S, Knoell DL, Woodiga SA, King SJ, Wewers MD 
In:
PLoS ONE (2016) 11(9): doi: 10.1371/journal.pone.0161931 
3D Reconstruction of the Human Airway Mucosa In Vitro as an Experimental Model to Study NTHi Infections.
Categories:
Primary Cells and Media 
Authors:
Marrazzo P, Maccari S, Taddei A, Bevan L, Telford J, Soriani M, Pezzicoli A 
In:
PLoS ONE (2016) 11(4): e0153985 
Unjamming and cell shape in the asthmatic airway epithelium
Categories:
Primary Cells and Media 
Authors:
Park JA, Kim JH, Bi D, Mitchel JA, Qazvini NT, Tantisira K, Park CY, McGill M, Kim SH, Gweon B, Notbohm J, Steward R Jr, Burger S, Randell SH, Kho AT, Tambe DT, Hardin C, Shore SA, Israel E, Weitz DA, Tschumperlin DJ, Henske EP, Weiss ST, Manning ML, Butler JP, Drazen JM, Fredberg JJ 
In:
Other (2015) 14(10): 1040-8 
Bacillus anthracis spores germinate extracellularly at air-liquid interface in an in vitro lung model under serum-free conditions.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Powell JD, Hutchison JR, Hess BM, Straub TM 
In:
Other (2015) 119(3): 711-23 
Comprehensive evaluation of poly(I:C) induced inflammatory response in an airway epithelial model
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Lever AR, Park H, Mulhern TJ, Jackson GR, Comolli JC, Borenstein JT, Hayden PJ, Prantil-Baun R 
In:
Physiol Rep (2015) 3(4): e12334 
Cross-talk between PKA-Cß and p65 mediates synergistic induction of PDE4B by roflumilast and NTHi
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Susuki-Miyata S, Miyata M, Lee BC, Xu H, Kai H, Yan C, Li JD 
In:
Proc Natl Acad Sci USA (2015) 112(14): e1800-9 
TWEAK enhances TGF-ß-induced epithelial-mesenchymal transition in human bronchial epithelial cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Itoigawa Y, Harada N, Harada S, Katsura Y, Makino F, Ito J, Nurwidya F, Kato M, Takahashi F, Atsuta R, Takahashi K 
In:
Respir Res (2015) 16: 48 
Vitronectin expression in the airways of subjects with asthma and chronic obstructive pulmonary disease
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Salazar-Peláez LM, Abraham T, Herrera AM, Correa MA, Ortega JE, Paré PD, Seow CY 
In:
PLoS ONE (2015) 10(3): e0119717 
Identification and characterization of PERK activators by phenotypic screening and their effects on NRF2 activation
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Xie W, Pariollaud M, Wixted WE, Chitnis N, Fornwald J, Truong M, Pao C, Liu Y, Ames RS, Callahan J, Solari R, Sanchez Y, Diehl A, Li H 
In:
PLoS ONE (2015) 10(3): e0119738 
Paraquat induces epithelial-mesenchymal transition-like cellular response resulting in fibrogenesis and the prevention of apoptosis in human pulmonary epithelial cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Yamada A, Aki T, Unuma K, Funakoshi T, Uemura K 
In:
PLoS ONE (2015) 10(3): e0120192 
Tight junction disruption by cadmium in an in vitro human airway tissue model
Categories:
 
Authors:
Cao X, Lin H, Muskhelishvili L, Latendresse J, Richter P, Heflich RH 
In:
Respir Res (2015) 16: 30 
Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Furukawa M, Wheeler S, Clark AM, Wells A 
In:
PLoS ONE (2015) 10 (1): e0118060 
Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Miyata M, Lee JY, Susuki-Miyata S, Wang WY, Xu H, Kai H, Kobayashi KS, Flavell RA, Li JD 
In:
Nat Commun. (2015) 6: 6062 
In vitro reconstruction of branched tubular structures from lung epithelial cells in high cell concentration gradient environment
Categories:
Primary Cells and Media, 3D Cell Culture , Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Hagiwara M, Peng F, Ho CM 
In:
Scientific Reports (2015) 5: 8054 
The oxidative potential of differently charged silver and gold nanoparticles on three human lung epithelial cell types
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Schlinkert P, Casals E, Boyles M, Tischler U, Hornig E, Tran N, Zhao J, Himly M, Riediker M, Oostingh GJ, Puntes V, Duschl A 
In:
J Nanobiotechnology (2015) 13: 1 
Directional secretory response of double stranded RNA-induced thymic stromal lymphopoetin (TSLP) and CCL11/eotaxin-1 in human asthmatic airways
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Nino G, Huseni S, Perez GF, Pancham K, Mubeen H, Abbasi A, Wang J, Eng S, Colberg-Poley AM, Pillai DK, Rose MC 
In:
PLoS ONE (2014) 9(12): e115398 
Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Liedmann S, Hrincius ER, Guy C, Anhlan D, Dierkes R, Carter R, Wu G, Staeheli P, Green DR, Wolff T, McCullers JA, Ludwig S, Ehrhardt C 
In:
Nat Commun. (2014) 5: 5645 
Role of serine proteases in the regulation of interleukin-877 during the development of bronchopulmonary dysplasia in preterm ventilated infants
Categories:
 
Authors:
Chakraborty M, McGreal EP, Williams A, Davies PL, Powell W, Abdulla S, Voitenok NN, Hogwood J, Gray E, Spiller B, Chambers RC, Kotecha S 
In:
PLoS ONE (2014) 9(12): e114524 
Cysteamine (Lynovex®), a novel mucoactive antimicrobial & antibiofilm agent for the treatment of cystic fibrosis
Categories:
Primary Cells and Media 
Authors:
Charrier C, Rodger C, Robertson J, Kowalczuk A, Shand N, Fraser-Pitt D, Mercer D, O'Neil D 
In:
Orphanet Journal of Rare Diseases (2014) 30(9): 189 
Polymerase discordance in novel swine influenza H3N2v constellations is tolerated in swine but not human respiratory epithelial cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Powell JD, Dlugolenski D, Nagy T, Gabbard J, Lee C, Tompkins SM, Tripp RA 
In:
PLoS ONE (2014) 9(10): e110264 
High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Seng LG, Daly J, Chang KC, Kuchipudi SV 
In:
PLoS ONE (2014) 9(10): e109023 
Refining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genes
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Meng J, Lee S, Hotard AL, Moore ML 
In:
mBio (2014) 5(5): e01704-14 
Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae ß-galactosidase, BgaA
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Singh AK, Pluvinage B, Higgins MA, Dalia AB, Woodiga SA, Flynn M, Lloyd AR, Weiser JN, Stubbs KA, Boraston AB, King SJ 
In:
PLoS Pathog (2014) 10(9): e1004364 
Folliculin regulates cell-cell adhesion, AMPK, and mTORC1 in a cell-type-specific manner in lung-derived cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Khabibullin D, Medvetz DA, Pinilla M, Hariharan V, Li C, Hergrueter A, Laucho Contreras M, Zhang E, Parkhitko A, Yu JJ, Owen CA, Huang H, Baron RM, Henske EP 
In:
Respir Res (2014) 2(8): e12107 
Dectin-1 is expressed in human lung and mediates the proinflammatory immune response to nontypeable Haemophilus influenzae
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Heyl KA, Klassert TE, Heinrich A, Müller MM, Klaile E, Dienemann H, Grünewald C, Bals R, Singer BB, Slevogt H 
In:
mBio (2014) 5(5): e01492-14 
Antimycobacterial drugs modulate immunopathogenic matrix metalloproteinases in a cellular model of pulmonary tuberculosis
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Singh S, Kubler A, Singh UK, Singh A, Gardiner H, Prasad R, Elkington PT, Friedland JS 
In:
Antimicrob Agents Chemother (2014) 58(8): 4657-65 
Nerve growth factor reduces amiloride-sensitive Na+ transport in human airway epithelial cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Shimko MJ, Zaccone EJ, Thompson JA, Schwegler-Berry D, Kashon ML, Fedan JS 
In:
Physiol Rep (2014) 2(7): e12073 
The Moraxella catarrhalis-induced pro-inflammatory immune response is enhanced by the activation of the epidermal growth factor receptor in human pulmonary epithelial cells
Categories:
Primary Cells and Media 
Authors:
N\\\'Guessan PD, Haarmann H, Steiner T, Heyl K, Schreiber F, Heinrich A, Slevogt H 
In:
Biochem Biophys Res Commun (2014) 450(2): 1038-44 
Novel roles of focal adhesion kinase in cytoplasmic entry and replication of influenza A viruses
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Elbahesh H, Cline T, Baranovich T, Govorkova EA, Schultz-Cherry S, Russell CJ 
In:
J Virol (2014) 88(12): 6714-28 
Bronchial epithelial cells are rendered insensitive to glucocorticoid transactivation by transforming growth factor-ß1
Categories:
Primary Cells and Media 
Authors:
Keenan CR, Mok JS, Harris T, Xia Y, Salem S, Stewart AG 
In:
Respir Res (2014) 1 (15): 55 
Bronchial epithelial cells are rendered insensitive to glucocorticoid transactivation by transforming growth factor-ß1.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Keenan CR, Mok JS, Harris T, Xia Y, Salem S, Stewart AG 
In:
Respir Res (2014) 15(55): 1-15 
Brd4 is essential for IL-1ß-induced inflammation in human airway epithelial cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Khan YM, Kirkham P, Barnes PJ, Adcock IM 
In:
PLoS ONE (2014) 9(4): e95051 
Characterization of an autotransporter adhesin protein shared by Burkholderia mallei and Burkholderia pseudomallei
Categories:
Primary Cells and Media 
Authors:
Lafontaine ER, Balder R, Michel F, Hogan RJ 
In:
BMC Microbiol. (2014) 14: 92 
Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media, Transfection 
Authors:
Singer BB, Opp L, Heinrich A, Schreiber F, Binding-Liermann R, Berrocal-Almanza LC, Heyl KA, Müller MM, Weimann A, Zweigner J, Slevogt H 
In:
PLoS ONE (2014) 9(4): e94106 
Low-solubility particles and a Trojan-horse type mechanism of toxicity: the case of cobalt oxide on human lung cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Ortega R, Bresson C, Darolles C, Gautier C, Roudeau S, Perrin L, Janin M, Floriani M, Aloin V, Carmona A, Malard V 
In:
Particle and Fibre Toxicology (2014) 11: 14 
Respiratory syncytial virus infection, TLR3 ligands, and proinflammatory cytokines induce CD161 ligand LLT1 expression on the respiratory epithelium
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Satkunanathan S, Kumar N, Bajorek M, Purbhoo MA, Culley FJ 
In:
J Virol (2014) 88(5): 2366-73 
A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Llop-Guevara A1, Chu DK1, Walker TD1, Goncharova S1, Fattouh R1, Silver JS2, Moore CL1, Xie JL1, O'Byrne PM3, Coyle AJ4, Kolbeck R2, Humbles AA2, Stämpfli MR5, Jordana M1. 
In:
PLoS ONE (2014) 9(2): e88714 
In vitro spatial and temporal analysis of Mycoplasma pneumoniae colonization of human airway epithelium
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Prince OA, Krunkosky TM, Krause DC 
In:
Infect Immun (2014) 82(2): 579-86 
Digoxin net secretory transport in bronchial epithelial cell layers is not exclusively mediated by P-glycoprotein/MDR1.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Hutter V1, Chau DY2, Hilgendorf C3, Brown A4, Cooper A5, Zann V5, Pritchard DI4, Bosquillon C6. 
In:
Eur J Pharm Biopharm (2014) 86(1): 74-82 
Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Onoufriadis A1, Shoemark A, Munye MM, James CT, Schmidts M, Patel M, Rosser EM, Bacchelli C, Beales PL, Scambler PJ, Hart SL, Danke-Roelse JE, Sloper JJ, Hull S, Hogg C, Emes RD, Pals G, Moore AT, Chung EM; UK10K, Mitchison HM. 
In:
Other (2014) 51(1): 61-7 
Stimulated bronchial epithelial cells release bioactive lysophosphatidylcholine 16:0, 18:0, and 18:1.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Zhuge Y1, Yuan Y2, van Breemen R2, Degrand M1, Holian O1, Yoder M3, Lum H1. 
In:
Allergy Asthma Immunol Res. (2014) 6(1): 66-74 
Bosutinib inhibits migration and invasion via ACK1 in KRAS mutant non-small cell lung cancer
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Tan DS, Haaland B, Gan JM, Tham SC, Sinha I, Tan EH, Lim KH, Takano A, Krisna SS, Thu MM, Liew HP, Ullrich A, Lim WT, Chua BT 
In:
Mol Cancer (2014) 13: 13 
Progranulin is a substrate for neutrophil-elastase and proteinase-3 in the airway and its concentration correlates with mediators of airway inflammation in COPD
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Ungurs MJ, Sinden NJ, Stockley RA 
In:
Am J Physiol Lung Cell Mol Physiol (2014) 306(1): L80-7 
Cytokine-Induced Loss of Glucocorticoid Function: Effect of Kinase Inhibitors, Long- Acting ß2-Adrenoceptor Agonist and Glucocorticoid Receptor Ligands
Categories:
Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Christopher F. Rider, Suharsh Shah, Anna Miller-Larsson, Mark A. Giembycz, Robert Newton1 
In:
PLoS ONE (2014) 10(1): e0116773 
Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Alayev A, Sun Y, Snyder RB, Berger SM, Yu JJ, Holz MK 
In:
Cell Cycle. (2013) 13(3): 371-82 
Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity
Categories:
Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Walters MS, Gomi K, Ashbridge B, Moore MA, Arbelaez V, Heldrich J, Ding BS, Rafii S, Staudt MR, Crystal RG 
In:
Respir Res (2013) 14(135): 10.1186/1465-9921-14-135 
Quantitative assessment of biological impact using transcriptomic data and mechanistic network models.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Thomson TM1, Sewer A, Martin F, Belcastro V, Frushour BP, Gebel S, Park J, Schlage WK, Talikka M, Vasilyev DM, Westra JW, Hoeng J, Peitsch MC 
In:
Toxicol Appl Pharmacol (2013) 272(3): 863-78 
Pro-resolution mediator lipoxin A4 and its receptor in upper airway inflammation.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Shimizu S, Ogawa T, Seno S, Kouzaki H, Shimizu T. 
In:
Ann Otol Rhinol Laryngol. (2013) 122(11): 683-9 
Early host responses of seasonal and pandemic influenza A viruses in primary well-differentiated human lung epithelial cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Gerlach RL, Camp JV, Chu YK, Jonsson CB 
In:
PLoS ONE (2013) 8(11): e78912 
HIV gp120 induces mucus formation in human bronchial epithelial cells through CXCR4/a7-nicotinic acetylcholine receptors.
Categories:
Primary Cells and Media 
Authors:
Gundavarapu S, Mishra NC, Singh SP, Langley RJ, Saeed AI, Feghali-Bostwick CA, McIntosh JM, Hutt J, Hegde R, Buch S, Sopori ML 
In:
PLoS ONE (2013) 8(10): e77160 
Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Pothlichet J1, Meunier I, Davis BK, Ting JP, Skamene E, von Messling V, Vidal SM. 
In:
PLoS Pathog (2013) 4: e1003256. 
The nitrated fatty acid 10-nitro-oleate attenuates allergic airway disease.
Categories:
Primary Cells and Media 
Authors:
Reddy AT, Lakshmi SP, Dornadula S, Pinni S, Rampa DR, Reddy RC. 
In:
J Immunol (2013) 191(5): 2053-63 
Regulation of CYP3A genes by glucocorticoids in human lung cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Roberts JK1, Moore CD1, Romero EG1, Ward RM2, Yost GS1, Reilly CA1. 
In:
Other (2013) 2: 173 
Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II interferons.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Klaile E1, Klassert TE, Scheffrahn I, Müller MM, Heinrich A, Heyl KA, Dienemann H, Grünewald C, Bals R, Singer BB, Slevogt H. 
In:
Respir Res (2013) 14: 85 
Highly pathogenic H5N1 influenza A virus strains provoke heterogeneous IFN-a/ß responses that distinctively affect viral propagation in human cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Matthaei M1, Budt M, Wolff T. 
In:
PLoS ONE (2013) 8(2): e56659 
Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human bronchial epithelial cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Foster HA, Estrada-Girona G, Themis M, Garimberti E, Hill MA, Bridger JM, Anderson RM 
In:
Mutat Res (2013) 756(1-2): 66-77 
Pyocyanin-induced mucin production is associated with redox modification of FOXA2.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Hao Y1, Kuang Z, Xu Y, Walling BE, Lau GW. 
In:
Respir Res (2013) 14: 82 
The Secretome of Human Bronchial Epithelial Cells Exposed to Fine Atmospheric Particles Induces Fibroblast Proliferation
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Boublil L, Martinon L, Baeza-Squiban A 
In:
Other (2013) 4(2): 188-200 
Normal CFTR inhibits epidermal growth factor receptor-dependent pro-inflammatory chemokine production in human airway epithelial cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Kim S, Beyer BA, Lewis C, Nadel JA 
In:
PLoS ONE (2013) 8(8): e72981 
Immune mediators regulate CFTR expression through a bifunctional airway-selective enhancer
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Zhang Z, Leir SH, Harris A 
In:
Mol Cell Biol (2013) 33(15): 2843-53 
Systematic verification of upstream regulators of a computable cellular proliferation network model on non-diseased lung cells using a dedicated dataset.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Belcastro V1, Poussin C, Gebel S, Mathis C, Schlage WK, Lichtner RB, Quadt-Humme S, Wagner S, Hoeng J, Peitsch MC. 
In:
Bioinform Biol Insights (2013) 7: 217-30 
Genome-wide RNAi screen reveals a new role of a WNT/CTNNB1 signaling pathway as negative regulator of virus-induced innate immune responses.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Baril M, Es-Saad S, Chatel-Chaix L, Fink K, Pham T, Raymond VA, Audette K, Guenier AS, Duchaine J, Servant M, Bilodeau M, Cohen E, Grandvaux N, Lamarre D 
In:
PLoS Pathog (2013) 9(6): e1003416 
The effect of lung cancer on cytokine expression in peripheral blood mononuclear cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Chang DH, Rutledge JR, Patel AA, Heerdt BG, Augenlicht LH, Korst RJ. 
In:
PLoS ONE (2013) 8(6): e64456 
PRISM offers a comprehensive genomic approach to transcription factor function prediction
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Wenger AM, Clarke SL, Guturu H, Chen J, Schaar BT, McLean CY, Bejerano G. 
In:
Genome Res (2013) 23(5): 889-904 
The role of interleukin-1 and interleukin-18 in pro-inflammatory and anti-viral responses to rhinovirus in primary bronchial epithelial cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Piper SC1, Ferguson J, Kay L, Parker LC, Sabroe I, Sleeman MA, Briend E, Finch DK. 
In:
PLoS ONE (2013) 8(5): e63365 
PRC2 overexpression and PRC2-target gene repression relating to poorer prognosis in small cell lung cancer
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Sato T, Kaneda A, Tsuji S, Isagawa T, Yamamoto S, Fujita T, Yamanaka R, Tanaka Y, Nukiwa T, Marquez VE, Ishikawa Y, Ichinose M, Aburatani H 
In:
Scientific Reports (2013) 3: 1911 
Inducible tumor necrosis factor (TNF) receptor-associated factor-1 expression couples the canonical to the non-canonical NF-?B pathway in TNF stimulation
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Choudhary S, Kalita M, Fang L, Patel KV, Tian B, Zhao Y, Edeh CB, Brasier AR 
In:
J Biol Chem (2013) 288(20): 14612-23 
Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Komatsu K1, Lee JY, Miyata M, Hyang Lim J, Jono H, Koga T, Xu H, Yan C, Kai H, Li JD. 
In:
Nat Commun. (2013) 4: 1684 
Reassortment between Avian H5N1 and human influenza viruses is mainly restricted to the matrix and neuraminidase gene segments
Categories:
Primary Cells and Media, Classical Media and Reagents 
Authors:
Schrauwen EJ, Bestebroer TM, Rimmelzwaan GF, Osterhaus AD, Fouchier RA, Herfst S. 
In:
PLoS ONE (2013) 8(3):: 10.1371/journal.pone.0059889 
Nucleosome mapping across the CFTR locus identifies novel regulatory factors
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Yigit E, Bischof JM, Zhang Z, Ott CJ, Kerschner JL, Leir SH, Buitrago-Delgado E, Zhang Q, Wang JP, Widom J, Harris A. 
In:
Nucleic Acids Res (2013) 41(5): 2857-68 
Gene mutation in microRNA target sites of CFTR gene: a novel pathogenetic mechanism in cystic fibrosis?
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Amato F1, Seia M, Giordano S, Elce A, Zarrilli F, Castaldo G, Tomaiuolo R 
In:
PLoS ONE (2013) 8(3): 60448 
Development of a repeated exposure protocol of human bronchial epithelium in vitro to study the long-term effects of atmospheric particles.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Boublil L1, Assémat E, Borot MC, Boland S, Martinon L, Sciare J, Baeza-Squiban A. 
In:
Toxicol In Vitro (2013) 27(2): 533-42 
Mir-21 Regulation of MARCKS Protein and Mucin Secretion in Airway Epithelial Cellsuery )
Categories:
Primary Cells and Media 
Authors:
W. Randall Lampe, Shijing Fang, Qi Yin, Anne L. Crews, Joungjoa Park, Kenneth B. Adler 
In:
Journal of Respiratory Diseases (2013) 3: 89-96 
Influenza A virus nucleoprotein induces apoptosis in human airway epithelial cells: implications of a novel interaction between nucleoprotein and host protein Clusterin
Categories:
Primary Cells and Media 
Authors:
Tripathi S, Batra J, Cao W, Sharma K, Patel JR, Ranjan P, Kumar A, Katz JM, Cox NJ, Lal RB, Sambhara S, Lal SK 
In:
Cell Death Dis. (2013) 4: e562 
IL-22 suppresses IFN-gamma-mediated lung inflammation in asthmatic patients
Categories:
Primary Cells and Media 
Authors:
Pennino D, Bhavsar PK, Effner R, Avitabile S, Venn P, Quaranta M, Marzaioli V, Cifuentes L, Durham SR, Cavani A, Eyerich K, Chung KF, Schmidt-Weber CB, Eyerich S. 
In:
J Allergy Clin Immunol (2013) 131(2): 562-70 
Silica induces NLRP3 inflammasome activation in human lung epithelial cells.
Categories:
Primary Cells and Media 
Authors:
Peeters PM, Perkins TN, Wouters EF, Mossman BT, Reynaert NL. 
In:
Particle and Fibre Toxicology (2013) 10:3: 1-11 
Response of Differentiated Human Airway Epithelia to Alcohol Exposure and Klebsiella pneumoniae Challenge
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Sammeta V. Raju, Richard G. Painter, Gregory J. Bagby, Steve Nelson and Guoshun Wang 
In:
Med. Sci. (2013) 1: 2-19 
Postexposure application of Fas receptor small-interfering RNA to suppress sulfur mustard-induced apoptosis in human airway epithelial cells: implication for a therapeutic approach
Categories:
Primary Cells and Media 
Authors:
Keyser BM, Andres DK, Nealley E, Holmes WW, Benton B, Paradiso D, Appell A, Carpin C, Anderson DR, Smith WJ, Ray R. 
In:
J Pharmacol Exp Ther (2013) 344(1): 308-16 
Evaluation of layers of the rat airway epithelial cell line RL-65 for permeability screening of inhaled drug candidates
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Hutter V, Hilgendorf C, Cooper A, Zann V, Pritchard DI, Bosquillon C. 
In:
Eur J Pharm Sci (2012) 47(2): 481-9 
Identification of novel deregulated RNA metabolism-related genes in non-small cell lung cancer
Categories:
Primary Cells and Media, Bioassay  
Authors:
Valles I, Pajares MJ, Segura V, Guruceaga E, Gomez-Roman J, Blanco D, Tamura A, Montuenga LM, Pio R. 
In:
PLoS ONE (2012) Identificati: 7(8) 
Molecular mechanisms controlling CFTR gene expression in the airway.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Zhang Z, Ott CJ, Lewandowska MA, Leir SH, Harris A. 
In:
J Cell Mol Med (2012) 16(6): 1321-30 
Characterization of extended co-culture of non-typeable Haemophilus influenzae with primary human respiratory tissues
Categories:
Primary Cells and Media 
Authors:
Ren D, Nelson KL, Uchakin PN, Smith AL, Gu XX, Daines DA. 
In:
Exp Biol Med (2012) 237(5): 540-7 
Biological roles of nontypeable Haemophilus influenzae type IV pilus proteins encoded by the pil and com operons
Categories:
Primary Cells and Media, Classical Media and Reagents, Electrophoreses and Analysis  
Authors:
Carruthers MD, Tracy EN, Dickson AC, Ganser KB, Munson RS Jr, Bakaletz LO 
In:
Journal of Bacteriology (2012) 194(8): 1927-33 
Changes in expression of drug-metabolizing enzymes by single-walled carbon nanotubes in human respiratory tract cells.
Categories:
Primary Cells and Media 
Authors:
Hitoshi K, Katoh M, Suzuki T, Ando Y, Nadai M. 
In:
Drug Metabolism and Disposition (2012) 40(3): 579-87 
Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells.
Categories:
Primary Cells and Media 
Authors:
Perkins TN, Shukla A, Peeters PM, Steinbacher JL, Landry CC, Lathrop SA, Steele C, Reynaert NL, Wouters EF, Mossman BT. 
In:
Particle and Fibre Toxicology (2012) 9(1): 6 
Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury.
Categories:
Primary Cells and Media 
Authors:
Thomas KC, Roberts JK, Deering-Rice CE, Romero EG, Dull RO, Lee J, Yost GS, Reilly CA. 
In:
Am J Physiol Lung Cell Mol Physiol (2012) 302(1):: L111-9 
Evaluation of differentiated human bronchial epithelial cell culture systems for asthma research.
Categories:
Primary Cells and Media 
Authors:
Stewart CE, Torr EE, Mohd Jamili NH, Bosquillon C, Sayers I. 
In:
Journal of Allergy (2012) 2012:943982: 10.1155/2012/943982 
Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells.
Categories:
Primary Cells and Media, Electrophoreses and Analysis  
Authors:
Jing Y, Liu LZ, Jiang Y, Zhu Y, Guo NL, Barnett J, Rojanasakul Y, Agani F, Jiang BH. 
In:
Toxicol Sci (2012) 125(1): 10-9 
Alternaria-induced release of IL-18 from damaged airway epithelial cells: an NF-?B dependent mechanism of Th2 differentiation?
Categories:
Primary Cells and Media 
Authors:
Murai H, Qi H, Choudhury B, Wild J, Dharajiya N, Vaidya S, Kalita A, Bacsi A, Corry D, Kurosky A, Brasier A, Boldogh I, Sur S. 
In:
PLoS ONE (2012) 7(2): e30280 
Nucleosome occupancy reveals regulatory elements of the CFTR promoter.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Ott CJ, Bischof JM, Unti KM, Gillen AE, Leir SH, Harris A. 
In:
Nucleic Acids Res (2012) 40(2): 625-37 
Adenovirus-mediated sensitization to the cytotoxic drugs docetaxel and mitoxantrone is dependent on regulatory domains in the E1ACR1 gene-region.
Categories:
Primary Cells and Media 
Authors:
Miranda E, Maya Pineda H, Öberg D, Cherubini G, Garate Z, Lemoine NR, Halldén G 
In:
PLoS ONE (2012) 7(10): 46617 
Hepcidin expression in human airway epithelial cells is regulated by interferon-gamma.
Categories:
Primary Cells and Media 
Authors:
Frazier MD, Mamo LB, Ghio AJ, Turi JL. 
In:
Respir Res (2011) 12:100: 10.1186/1465-9921-12-100 
Induction of inflammatory cytokines and toll-like receptors in human normal respiratory epithelial cells infected with seasonal H1N1, 2009 pandemic H1N1, seasonal H3N2, and highly pathogenic H5N1 influenza virus.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Song BM, Kang YM, Kim HS, Seo SH. 
In:
Zebrafish (2011) 24(3): 179-87 
Inhibition of histone lysine methylation enhances cancer-testis antigen expression in lung cancer cells: implications for adoptive immunotherapy of cancer.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Rao M1, Chinnasamy N, Hong JA, Zhang Y, Zhang M, Xi S, Liu F, Marquez VE, Morgan RA, Schrump DS. 
In:
Cancer Res (2011) 71(12): 4192-204 
Human bronchial epithelial cells differentiate to 3D glandular acini on basement membrane matrix.
Categories:
Primary Cells and Media, 3D Cell Culture , Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Wu X, Peters-Hall JR, Bose S, Peña MT, Rose MC 
In:
Am J Respir Cell Mol Biol (2011) 44(6): 914-21 
The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury
Categories:
Primary Cells and Media 
Authors:
Funke M, Zhao Z, Xu Y, Chun J, Tager AM 
In:
Am J Respir Cell Mol Biol (2011) 46(3): 355-64 
Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
March C, Moranta D, Regueiro V, Llobet E, Tomás A, Garmendia J, Bengoechea JA. 
In:
J Biol Chem (2011) 286(12): 9956-67 
Up-regulation of sonic hedgehog contributes to TGF-ß1-induced epithelial to mesenchymal transition in NSCLC cells
Categories:
Primary Cells and Media 
Authors:
Maitah MY, Ali S, Ahmad A, Gadgeel S, Sarkar FH. 
In:
PLoS ONE (2011) 6(1): e16068 
Regulation of apoptotic effects by erythrocarpine E, a cytotoxic limonoid from Chisocheton erythrocarpus in HSC-4 human oral cancer cells
Categories:
Primary Cells and Media, Classical Media and Reagents 
Authors:
Nagoor NH, Shah Jehan Muttiah N, Lim CS, In LL, Mohamad K, Awang K. 
In:
PLoS ONE (2011) 6(8): e23661 
Direct measurement of oxygen consumption rates from attached and unattached cells in a reversibly sealed, diffusionally isolated sample chamber.
Categories:
Primary Cells and Media 
Authors:
Strovas TJ, McQuaide SC, Anderson JB, Nandakumar V, Kalyuzhnaya MG, Burgess LW, Holl MR, Meldrum DR, Lidstrom ME. 
In:
Adves in Bioscince and Biotechnology (2010) 5(5): 398-408 
IL-33 Mediates Inflammatory Responses in Human Lung Tissue Cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Yagami A, Orihara K, Morita H, Futamura K, Hashimoto N, Matsumoto K, Saito H, Matsuda A. 
In:
J Immunol (2010) 185(10): 5743-50 
A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma
Categories:
Primary Cells and Media 
Authors:
Wang YH, Voo KS, Liu B, Chen CY, Uygungil B, Spoede W, Bernstein JA, Huston DP, Liu YJ 
In:
J Exp Med (2010) 207(11): 2479-91 
The oncoprotein SF2/ASF promotes non-small cell lung cancer survival by enhancing survivin expression.
Categories:
Primary Cells and Media 
Authors:
Ezponda T, Pajares MJ, Agorreta J, Echeveste JI, López-Picazo JM, Torre W, Pio R, Montuenga LM. 
In:
Clin Cancer Res (2010) 16(16): 4113-25 
MARCKS and related chaperones bind to unconventional myosin V isoforms in airway epithelial cells
Categories:
Primary Cells and Media 
Authors:
Lin KW, Fang S, Park J, Crews AL, Adler KB. 
In:
Am J Respir Cell Mol Biol (2010) 43(2): 131-6 
Respiratory syncytial virus F and G proteins induce interleukin 1alpha, CC, and CXC chemokine responses by normal human bronchoepithelial cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Oshansky CM, Barber JP, Crabtree J, Tripp RA. 
In:
J Infect Dis (2010) 201(8): 1201-7 
Dissection of host cell signal transduction during Acinetobacter baumannii-triggered inflammatory response.
Categories:
Primary Cells and Media 
Authors:
March C, Regueiro V, Llobet E, Moranta D, Morey P, Garmendia J, Bengoechea JA. 
In:
PLoS ONE (2010) 5(4): e10033 
Influenza H5N1 and H1N1 virus replication and innate immune responses in bronchial epithelial cells are influenced by the state of differentiation
Categories:
Primary Cells and Media 
Authors:
Chan RW, Yuen KM, Yu WC, Ho CC, Nicholls JM, Peiris JS, Chan MC. 
In:
PLoS ONE (2010) 5(1): e8713 
Improved potency and selectivity of an oncolytic E1ACR2 and E1B19K deleted adenoviral mutant in prostate and pancreatic cancers.
Categories:
Primary Cells and Media 
Authors:
Oberg D, Yanover E, Adam V, Sweeney K, Costas C, Lemoine NR, Halldén G. 
In:
Clin Cancer Res (2010) 16(2): 541-53 
Integrative discovery of epigenetically derepressed cancer testis antigens in NSCLC
Categories:
Primary Cells and Media 
Authors:
Glazer CA, Smith IM, Ochs MF, Begum S, Westra W, Chang SS, Sun W, Bhan S, Khan Z, Ahrendt S, Califano JA. 
In:
PLoS ONE (2009) 4(12): e8189 
TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids
Categories:
Primary Cells and Media 
Authors:
Doerner AM, Zuraw BL 
In:
Respir Res (2009) 10:100: 10.1186/1465-9921-10-100 
Airway epithelium stimulates smooth muscle proliferation
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Malavia NK, Raub CB, Mahon SB, Brenner M, Panettieri RA Jr, George SC. 
In:
Am J Respir Cell Mol Biol (2009) 41(3): 297-304 
Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system
Categories:
Primary Cells and Media 
Authors:
Kadara H, Lacroix L, Behrens C, Solis L, Gu X, Lee JJ, Tahara E, Lotan D, Hong WK, Wistuba II, Lotan R. 
In:
Cancer Res (2009) 2(8): 702-11 
Arginine deficiency augments inflammatory mediator production by airway epithelial cells in vitro.
Categories:
Primary Cells and Media 
Authors:
Fan XY, van den Berg A, Snoek M, van der Flier LG, Smids B, Jansen HM, Liu RY, Lutter R. 
In:
Respir Res (2009) 10: 62 
Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells.
Categories:
Primary Cells and Media 
Authors:
Luxen S, Noack D, Frausto M, Davanture S, Torbett BE, Knaus UG 
In:
J Cell Sci (2009) 122(Pt 8): 1238-47 
Cigarette smoke extract reduces VEGF in primary human airway epithelial cells
Categories:
Primary Cells and Media 
Authors:
Thaikoottathil JV, Martin RJ, Zdunek J, Weinberger A, Rino JG, Chu HW 
In:
Eur Respir J (2009) 33(4): 835-43 
Lung epithelial injury by B. anthracis lethal toxin is caused by MKK-dependent loss of cytoskeletal integrity
Categories:
Primary Cells and Media 
Authors:
Lehmann M, Noack D, Wood M, Perego M, Knaus UG. 
In:
PLoS ONE (2009) 4(3): e4755 
Oncolytic adenoviral mutants with E1B19K gene deletions enhance gemcitabine-induced apoptosis in pancreatic carcinoma cells and anti-tumor efficacy in vivo.
Categories:
Primary Cells and Media 
Authors:
Leitner S, Sweeney K, Oberg D, Davies D, Miranda E, Lemoine NR, Halldén G. 
In:
Clin Cancer Res (2009) 15(5): 1730-40 
Mechanical compression attenuates normal human bronchial epithelial wound healing
Categories:
Primary Cells and Media 
Authors:
Arold SP, Malavia N, George SC 
In:
Respir Res (2009) 10: 9 
Epithelial ICAM-1 and ICAM-2 regulate the egression of human T cells across the bronchial epithelium.
Categories:
Primary Cells and Media 
Authors:
Porter JC, Hall A. 
In:
FASEB J (2009) 23(2): 492-502 
Klebsiella pneumoniae increases the levels of Toll-like receptors 2 and 4 in human airway epithelial cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Regueiro V, Moranta D, Campos MA, Margareto J, Garmendia J, Bengoechea JA. 
In:
Infect Immun (2009) 77(2): 714-24 
Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer.
Categories:
Primary Cells and Media 
Authors:
Daskalos A, Nikolaidis G, Xinarianos G, Savvari P, Cassidy A, Zakopoulou R, Kotsinas A, Gorgoulis V, Field JK, Liloglou T. 
In:
International Journal Cancer (2009) 124(1): 81-7 
The atypical Rho GTPase RhoBTB2 is required for expression of the chemokine CXCL14 in normal and cancerous epithelial cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
McKinnon CM1, Lygoe KA, Skelton L, Mitter R, Mellor H. 
In:
Oncogene (2008) 27(54): 6856-65 
IL-13 induces a bronchial epithelial phenotype that is profibrotic
Categories:
Primary Cells and Media 
Authors:
Malavia NK, Mih JD, Raub CB, Dinh BT, George SC 
In:
Respir Res (2008) 09: 27 
Syk associates with clathrin and mediates phosphatidylinositol 3-kinase activation during human rhinovirus internalization
Categories:
Transfection 
Authors:
Lau C, Wang X, Song L, North M, Wiehler S, Proud D, Chow CW 
In:
J Immunol (2008) 180(2): 870-80 
The role of IFN-gamma in regulation of IFN-gamma-inducible protein 10 (IP-10) expression in lung epithelial cell and peripheral blood mononuclear cell co-cultures.
Categories:
Primary Cells and Media 
Authors:
Torvinen M, Campwala H, Kilty I. 
In:
Respir Res (2007) 8: 80 
Airway epithelial cells synthesize the lipid mediator 5-oxo-ETE in response to oxidative stress
Categories:
Primary Cells and Media 
Authors:
Erlemann KR, Cossette C, Gravel S, Lesimple A, Lee GJ, Saha G, Rokach J, Powell WS 
In:
Free Radic Biol Med (2007) 42(5): 654-64 
Epithelial-derived TGF-beta2 modulates basal and wound-healing subepithelial matrix homeostasis.
Categories:
Primary Cells and Media 
Authors:
Thompson HG, Mih JD, Krasieva TB, Tromberg BJ, George SC. 
In:
Am J Physiol Lung Cell Mol Physiol (2006) 291(6): 1277-85 
Cutting Edge: Enhanced Pulmonary Clearance of Pseudomonas aeruginosa by Muc1 Knockout Mice
Categories:
Transfection 
Authors:
Lu W, Hisatsune A, Koga T, Kato K, Kuwahara I, Lillehoj EP, Chen W, Cross AS, Gendler SJ, Gewirtz AT, Kim KC 
In:
J Immunol (2006) 176(7): 3890-4 
Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Geiszt M, Witta J, Baffi J, Lekstrom K, Leto TL. 
In:
FASEB J (2003) 17(11): 1502-4 
Activating prostaglandin E2 receptor subtype EP4 increases secreted mucin from airway goblet cells.
Categories:
Primary Cells and Media 
Authors:
Akaba T1, Komiya K2, Suzaki I2, Kozaki Y2, Tamaoki J3, Rubin BK4 
In:
Other () 48: 117-123 
Crocin reduces Aspergillus fumigatus-induced airway inflammation and NF-?B signal activation.
Categories:
Primary Cells and Media 
Authors:
Du J1, Chi Y1, Song Z1, Di Q1, Mai Z1, Shi J1, Li M1 
In:
J Cell Biochem () 119: 1746-1754 
Host-directed combinatorial RNAi improves inhibition of diverse strains of influenza A virus in human respiratory epithelial cells.
Categories:
Primary Cells and Media 
Authors:
Estrin MA1, Hussein ITM1, Puryear WB1, Kuan AC1, Artim SC1, Runstadler JA1,2 
In:
PLoS ONE () 13: e0197246 
Epithelial disruption: a new paradigm enabling human airway stem cell transplantation.
Categories:
Primary Cells and Media 
Authors:
Farrow N1,2,3,4, Cmielewski P5,6,7, Donnelley M5,6,7, Rout-Pitt N5,6,7, Moodley Y8, Bertoncello I9, Parsons D5,6,7,10 
In:
Stem Cell Res Ther () 9: 153 
Innate Immunity Induced by the Major Allergen Alt a 1 From the Fungus Alternaria Is Dependent Upon Toll-Like Receptors 2/4 in Human Lung Epithelial Cells.
Categories:
Primary Cells and Media 
Authors:
Hayes T1,2, Rumore A3, Howard B1, He X1, Luo M1, Wuenschmann S4, Chapman M4, Kale S5, Li L1, Kita H6, Lawrence CB1 
In:
Frontiers in Immunology () 30: 1507 
Alteration in Claudin-4 Contributes to Airway Inflammation and Responsiveness in Asthma.
Categories:
Primary Cells and Media 
Authors:
Lee PH1, Kim BG1, Lee SH1, Lee JH1, Park SW1, Kim DJ1, Park CS1, Leikauf GD2, Jang AS3 
In:
Allergy Asthma Immunol Res. () 10: 25-33 
ß2-Adrenoceptor signaling in airway epithelial cells promotes eosinophilic inflammation, mucous metaplasia, and airway contractility
Categories:
Primary Cells and Media 
Authors:
Nguyen LP1, Al-Sawalha NA2, Parra S2, Pokkunuri I2, Omoluabi O3, Okulate AA2, Windham Li E1, Hazen M1, Gonzalez-Granado JM4, Daly CJ4, McGrath JC4, Tuvim MJ1, Knoll BJ2, Dickey BF1, Bond RA5 
In:
Proc Natl Acad Sci USA () 114: E9163-E9171 
MicroRNA expression profiling defines the impact of electronic cigarettes on human airway epithelial cells
Categories:
Primary Cells and Media 
Authors:
Solleti SK1, Bhattacharya S1, Ahmad A1, Wang Q1, Mereness J1,2, Rangasamy T3, Mariani TJ4,5,6 
In:
Scientific Reports () 7: 1081 
Inhibition of IL-13-induced periostin in airway epithelium attenuates cellular protein expression of MUC5AC.
Categories:
Primary Cells and Media 
Authors:
Suzaki I1,2, Kawano S1, Komiya K1, Tanabe T1, Akaba T1, Asano K3, Suzaki H4, Izuhara K5, Rubin BK1 
In:
Respir Res () 22: 93-100 
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