Endothelial, MV lung, human (HMVEC-L)

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Endothelial cells line the inside surface of blood vessels, heart, lymphatic vessels, body cavities and other organs, of normal human tissue.

Small vessel endothelial cells are isolated from lung microvascular tissue.

Cell Type:
Microvascular Endo.
Tissue Origin:
lung
Species:
human
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Research Area:
Cancer Research/Cell Biology
Cardiovascular
Cell Characteristics:
Adherent

Recommended Media

Endothelial Cell Growth Medium-2 Microvascular

EGM-2 MV has been developed for the enhanced growth of lung microvascular endothelial cells
Can be used to grow all Clonetics Endothelial cells except HUVEC
Final serum concentration is 5%
Does not contain BBE

Transfection Information

Lonza Optimized Protocol
Optimization Guideline
Filter:
The table below shows data for the cell type and Nucleofector™ Platform selected. Those data are either based on Lonza Optimized Protocols or on results shared from customers who performed an optimization based on our guidelines. In case no data are shown for the selected Nucleofector™ Platform, please take a look at our optimization strategy to get further guidance on how to easily determine optimal Nucleofection conditions yourself.
Protocol Kit Program Cells Efficiency Viable Cells Substrate Format Platform
P5

FP-100

 1e5 79% 48% Plasmid (general) 0.4 µg 20 µl 4D X-Unit
P5

96-FP-100

 1e5 75-83% 43-53% Plasmid (general) 0.4 µg 20 µl 96-well
HMVEC-L S-005 5e5 39-65% 43-61% Plasmid (general) 5 µg 100 µl I/II/2b

Citations (71)

Small interfering RNA inhibition of andes virus replication.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Chiang CF, Albarino CG, Lo MK, Spiropoulou CF. 
In:
PLoS ONE (2014) 9(6): e99764 
GRP78 is a novel receptor initiating a vascular barrier protective response to oxidized phospholipids.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Birukova AA, Singleton PA, Gawlak G, Tian X, Mirzapoiazova T, Mambetsariev B, Dubrovskyi O, Oskolkova OV, Bochkov VN, Birukov KG. 
In:
Mol Biol Cell (2014) mbc.E13: 12-0743 
Stiffness-Activated GEF-H1 Expression Exacerbates LPS-Induced Lung Inflammation.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Mambetsariev I, Tian Y, Wu T, Lavoie T, Solway J, Birukov KG, Birukova AA. 
In:
PLoS ONE (2014) 9(4): e92670 
Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Michalik KM, You X, Manavski Y, Doddaballapur A, Zörnig M, Braun T, John D, Ponomareva Y, Chen W, Uchida S, Boon RA, Dimmeler S. 
In:
Circ Res (2014) 114(9): 1389-97 
Effects of vascular endothelial growth factor on endothelin-1 production by human lung microvascular endothelial cells in vitro
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Star GP, Giovinazzo M, Lamoureux E, Langleben D 
In:
Other (2014) 14: 00289-6 
Regulation of NADPH oxidase 5 by protein kinase C isoforms.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Chen F, Yu Y, Haigh S, Johnson J, Lucas R, Stepp DW, Fulton DJ. 
In:
PLoS ONE (2014) 9(2): e88405 
Metabotropic glutamate receptor-1 as a novel target for the antiangiogenic treatment of breast cancer.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Speyer CL1, Hachem AH2, Assi AA2, Johnson JS3, DeVries JA4, Gorski DH5. 
In:
PLoS ONE (2014) 9(3):: e88830. 
Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Roberts LL, Robinson CM. 
In:
Immunology (2014) 141(1): 39 - 51 
Tumor stiffness is unrelated to myosin light chain phosphorylation in cancer cells
Categories:
Primary Cells and Media 
Authors:
Yu HJ1, Serebryannyy LA, Fry M, Greene M, Chernaya O, Hu WY, Chew TL, Mahmud N, Kadkol SS, Glover S, Prins G, Strakova Z, de Lanerolle P 
In:
PLoS ONE (2013) 8(11): e79776 
Muscle side population cells from dystrophic or injured muscle adopt a fibro-adipogenic fate
Categories:
Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Penton CM, Thomas-Ahner JM, Johnson EK, McAllister C, Montanaro F 
In:
PLoS ONE (2013) 08(1): e54553 
Ceramide synthases expression and role of ceramide synthase-2 in the lung: insight from human lung cells and mouse models
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Petrache I, Kamocki K, Poirier C, Pewzner-Jung Y, Laviad EL, Schweitzer KS, Van Demark M, Justice MJ, Hubbard WC, Futerman AH. 
In:
PLoS ONE (2013) 8(5): e62968 
Ceramide synthases expression and role of ceramide synthase-2 in the lung: insight from human lung cells and mouse models
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Petrache I, Kamocki K, Poirier C, Pewzner-Jung Y, Laviad EL, Schweitzer KS, Van Demark M, Justice MJ, Hubbard WC, Futerman AH 
In:
PLoS ONE (2013) 8(5): e62968 
Acidosis activation of the proton-sensing GPR4 receptor stimulates vascular endothelial cell inflammatory responses revealed by transcriptome analysis.
Categories:
Primary Cells and Media 
Authors:
Dong L, Li Z, Leffler NR, Asch AS, Chi JT, Yang LV. 
In:
PLoS ONE (2013) 8(4): e61991 
A role for PVRL4-driven cell-cell interactions in tumorigenesis
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Pavlova NN, Pallasch C, Elia AE, Braun CJ, Westbrook TF, Hemann M, Elledge SJ. 
In:
eLife (2013) 2: e00358 
ARFGEF2 Knockdown Enhances TNF-a Induced Endothelial Expression of the Cell Adhesion Molecules VCAM1 and ICAM1*
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Daniel A. Dworkis1,2, Elizabeth S. Klings1, Sherene M. Shenouda, Nadia Solovieff, Efthymia Melista, Carl Giovannucci, Surinder Safaya, Guihua Li, Joseph A. Vita, Martin H. Steinberg, Clinton T. Baldwin 
In:
Open Journal of Blood Diseases (2013) 3: 25-31 
Mitochondrial DAMPs increase endothelial permeability through neutrophil dependent and independent pathways.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Sun S, Sursal T, Adibnia Y, Zhao C, Zheng Y, Li H, Otterbein LE, Hauser CJ, Itagaki K. 
In:
PLoS ONE (2013) 8(3): e59989 
Host mTORC1 signaling regulates andes virus replication
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
McNulty S, Flint M, Nichol ST, Spiropoulou CF. 
In:
J Virol (2013) 87(2): 912-22 
A novel regulator of angiogenesis in endothelial cells: 5-hydroxytriptamine 4 receptor
Categories:
Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Profirovic J, Strekalova E, Urao N, Krbanjevic A, Andreeva AV, Varadarajan S, Fukai T, Hen R, Ushio-Fukai M, Voyno-Yasenetskaya TA 
In:
Angiogenesis (2013) 16(1): 15-28 
Staphylococcus epidermidis and Staphylococcus aureus trigger different interleukin-8 and intercellular adhesion molecule-1 in lung cells: implications for inflammatory complications following neonatal sepsis
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Ivarsson M, Schollin J, Björkqvist M 
In:
Acta Paediatr. (2012) 102(10): 1010-6 
Therapeutic Lymphangiogenesis With Implantation of Adipose-Derived Regenerative Cells
Categories:
Primary Cells and Media 
Authors:
Shimizu Y, Shibata R, Shintani S, Ishii M, Murohara T 
In:
J Am Heart Assoc (2012) 1(4): e000877 
Andes virus infection of lymphatic endothelial cells causes giant cell and enhanced permeability responses that are rapamycin and vascular endothelial growth factor C sensitive
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Gavrilovskaya IN, Gorbunova EE, Mackow ER 
In:
J Virol (2012) 86(16): 8765-72 
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Cross AS, Hyun SW, Miranda-Ribera A, Feng C, Liu A, Nguyen C, Zhang L, Luzina IG, Atamas SP, Twaddell WS, Guang W, Lillehoj EP, Puché AC, Huang W, Wang LX, Passaniti A, Goldblum SE. 
In:
J Biol Chem (2012) 287(19): 15966-80 
TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Liu A, Gong P, Hyun SW, Wang KZ, Cates EA, Perkins D, Bannerman DD, Puché AC, Toshchakov VY, Fang S, Auron PE, Vogel SN, Goldblum SE. 
In:
J Biol Chem (2012) 287(20): 16132-45 
Suppression of endothelial cell activity by inhibition of TNFa
Categories:
 
Authors:
Shu Q, Amin MA, Ruth JH, Campbell PL, Koch AE. 
In:
Arthritis Res Ther (2012) 14(2): R88 
ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Yuan L, Le Bras A, Sacharidou A, Itagaki K, Zhan Y, Kondo M, Carman CV, Davis GE, Aird WC, Oettgen P 
In:
J Biol Chem (2012) 287(9): 6582-91 
Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury.
Categories:
Primary Cells and Media 
Authors:
Thomas KC, Roberts JK, Deering-Rice CE, Romero EG, Dull RO, Lee J, Yost GS, Reilly CA. 
In:
Am J Physiol Lung Cell Mol Physiol (2012) 302(1):: L111-9 
A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses
Categories:
Primary Cells and Media 
Authors:
Gatheral T, Reed DM, Moreno L, Gough PJ, Votta BJ, Sehon CA, Rickard DJ, Bertin J, Lim E, Nicholson AG, Mitchell JA. 
In:
PLoS ONE (2012) 7(8): e42386 
Lung endothelial cell platelet-activating factor production and inflammatory cell adherence are increased in response to cigarette smoke component exposure
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Sharma J, Young DM, Marentette JO, Rastogi P, Turk J, McHowat J. 
In:
Am J Physiol Lung Cell Mol Physiol (2012) 301(1): L47-55 
Sonic Hedgehog Pathway Promotes Metastasis and Lymphangiogenesis via Activation of Akt, EMT, and MMP-9 Pathway in Gastric Cancer
Categories:
 
Authors:
Yoo YA1, Kang MH, Lee HJ, Kim BH, Park JK, Kim HK, Kim JS, Oh SC. 
In:
Cancer Res (2011) 71(22): 7061-70 
Thrombospondin-1 opens the paracellular pathway in pulmonary microvascular endothelia through EGFR/ErbB2 activation
Categories:
 
Authors:
Garg P, Yang S, Liu A, Pallero MA, Buchsbaum DJ, Mosher DF, Murphy-Ullrich JE, Goldblum SE 
In:
Am J Physiol Lung Cell Mol Physiol (2011) 301(1): L79-90 
Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Kuznik A, Bencina M, Svajger U, Jeras M, Rozman B, Jerala R. 
In:
J Immunol (2011) 186(8): 4794-804 
Vascular endothelial growth factor A (VEGF-A) induces endothelial and cancer cell migration through direct binding to integrin 91: identification of a specific 91 binding site.
Categories:
 
Authors:
Oommen S, Gupta SK, Vlahakis NE. 
In:
J Biol Chem (2011) 286(2): 1083-92 
NFAT and CREB regulate Kaposi's sarcoma-associated herpesvirus-induced cyclooxygenase 2 (COX-2)
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Sharma-Walia N, George Paul A, Patel K, Chandran K, Ahmad W, Chandran B 
In:
J Virol (2010) 84(24): 12733-53 
IL-33 Mediates Inflammatory Responses in Human Lung Tissue Cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Yagami A, Orihara K, Morita H, Futamura K, Hashimoto N, Matsumoto K, Saito H, Matsuda A. 
In:
J Immunol (2010) 185(10): 5743-50 
Role of synectin in lymphatic development in zebrafish and frogs
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Hermans K, Claes F, Vandevelde W, Zheng W, Geudens I, Orsenigo F, De Smet F, Gjini E, Anthonis K, Ren B, Kerjaschki D, Autiero M, Ny A, Simons M, Dewerchin M, Schulte-Merker S, Dejana E, Alitalo K, Carmeliet P. 
In:
Blood (2010) 116(17): 3356-66 
ZEB1 Coordinately Regulates Laminin-332 and 4 Integrin Expression Altering the Invasive Phenotype of Prostate Cancer Cells
Categories:
 
Authors:
Drake JM, Barnes JM, Madsen JM, Domann FE, Stipp CS, Henry MD. 
In:
J Biol Chem (2010) 285(44): 33940-8 
Adenosine receptor A1 regulates polymorphonuclear cell trafficking and microvascular permeability in lipopolysaccharide-induced lung injury
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Ngamsri KC, Wagner R, Vollmer I, Stark S, Reutershan J 
In:
J Immunol (2010) 185(7): 4374-84 
Adenosine receptor A3 is a critical mediator in LPS-induced pulmonary inflammation
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Wagner R, Ngamsri KC, Stark S, Vollmer I, Reutershan J. 
In:
Am J Physiol Lung Cell Mol Physiol (2010) 299(4): L502-12 
FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of beta-catenin expression
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Mirza MK, Sun Y, Zhao YD, Potula HH, Frey RS, Vogel SM, Malik AB, Zhao YY. 
In:
J Exp Med (2010) 207(8): 1675-85 
Netrin-4 induces lymphangiogenesis in vivo
Categories:
 
Authors:
Larrieu-Lahargue F, Welm AL, Thomas KR, Li DY. 
In:
Blood (2010) 115(26): 5418-26 
CADM1 interacts with Tiam1 and promotes invasive phenotype of human T-cell leukemia virus type I-transformed cells and adult T-cell leukemia cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Masuda M, Maruyama T, Ohta T, Ito A, Hayashi T, Tsukasaki K, Kamihira S, Yamaoka S, Hoshino H, Yoshida T, Watanabe T, Stanbridge EJ, Murakami Y. 
In:
J Biol Chem (2010) 285(20): 15511-22 
Signaling through the A2B adenosine receptor dampens endotoxin-induced acute lung injury
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Schingnitz U, Hartmann K, Macmanus CF, Eckle T, Zug S, Colgan SP, Eltzschig HK. 
In:
J Immunol (2010) 184(9): 5271-9 
The COOH-Terminal Peptide of Platelet Factor-4 Variant (CXCL4L1/PF-4var47-70) Strongly Inhibits Angiogenesis and Suppresses B16 Melanoma Growth In vivo
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Vandercappellen J, Liekens S, Bronckaers A, Noppen S, Ronsse I, Dillen C, Belleri M, Mitola S, Proost P, Presta M, Struyf S, Van Damme J. 
In:
Mol Cancer Res (2010) 8(3): 322-34 
Influence of the oxygen microenvironment on the proangiogenic potential of human endothelial colony forming cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Decaris ML, Lee CI, Yoder MC, Tarantal AF, Leach JK. 
In:
Angiogenesis (2009) 12(4): 303-11 
Filamin A regulates caveolae internalization and trafficking in endothelial cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Sverdlov M, Shinin V, Place AT, Castellon M, Minshall RD. 
In:
Mol Biol Cell (2009) 20(21): 4531-40 
Intermedin/adrenomedullin-2 is a hypoxia-induced endothelial peptide that stabilizes pulmonary microvascular permeability
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Pfeil U, Aslam M, Paddenberg R, Quanz K, Chang CL, Park JI, Gries B, Rafiq A, Faulhammer P, Goldenberg A, Papadakis T, Noll T, Hsu SY, Weissmann N, Kummer W. 
In:
Am J Physiol Lung Cell Mol Physiol (2009) 297(5): L837-45 
Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Jin N, Cho SN, Raso MG, Wistuba I, Smith Y, Yang Y, Kurie JM, Yen R, Evans CM, Ludwig T, Jeong JW, DeMayo FJ. 
In:
Development (2009) 136(19): 3347-56 
Erythromycin-induced CXCR4 expression on microvascular endothelial cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Takagi Y, Hashimoto N, Phan SH, Imaizumi K, Matsuo M, Nakashima H, Hashimoto I, Hayashi Y, Kawabe T, Shimokata K, Hasegawa Y. 
In:
Am J Physiol Lung Cell Mol Physiol (2009) 297(3): L420-31 
IL-6 cytoprotection in hyperoxic acute lung injury occurs via PI3K/Akt-mediated Bax phosphorylation.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Kolliputi N, Waxman AB. 
In:
Am J Physiol Lung Cell Mol Physiol (2009) 297(1): L6-16 
Kruppel-like Factor 2 Inhibits Hypoxia-inducible Factor 1 Expression and Function in the Endothelium*
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Kawanami D, Mahabeleshwar GH, Lin Z, Atkins GB, Hamik A, Haldar SM, Maemura K, Lamanna JC, Jain MK. 
In:
J Biol Chem (2009) 284(31): 20522-30 
alpha5beta1 Integrin blockade inhibits lymphangiogenesis in airway inflammation
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Okazaki T, Ni A, Ayeni OA, Baluk P, Yao LC, Vossmeyer D, Zischinsky G, Zahn G, Knolle J, Christner C, McDonald DM. 
In:
Am J Pathol (2009) 174(6): 2378-87 
Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Minegishi Y, Saito M, Nagasawa M, Takada H, Hara T, Tsuchiya S, Agematsu K, Yamada M, Kawamura N, Ariga T, Tsuge I, Karasuyama H. 
In:
J Exp Med (2009) 206(6): 1291-301 
Kaposi’s Sarcoma-Associated Herpesvirus Utilizes an Actin Polymerization-Dependent Macropinocytic Pathway To Enter Human Dermal Microvascular Endothelial andHuman Umbilical Vein Endothelial Cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Raghu H, Sharma-Walia N, Veettil MV, Sadagopan S, Chandran B. 
In:
J Virol (2009) 83(10): 4895-911 
ZEB1 Enhances Transendothelial Migration and Represses the Epithelial Phenotype of Prostate Cancer Cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Drake JM, Strohbehn G, Bair TB, Moreland JG, Henry MD. 
In:
Mol Biol Cell (2009) 20(8): 2207-17 
Identification of protein kinase D2 as a pivotal regulator of endothelial cell proliferation, migration, and angiogenesis
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Hao Q, Wang L, Zhao ZJ, Tang H. 
In:
J Biol Chem (2009) 284(2): 799-806 
Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Aleku M, Schulz P, Keil O, Santel A, Schaeper U, Dieckhoff B, Janke O, Endruschat J, Durieux B, Röder N, Löffler K, Lange C, Fechtner M, Möpert K, Fisch G, Dames S, Arnold W, Jochims K, Giese K, Wiedenmann B, Scholz A, Kaufmann J. 
In:
Cancer Res (2008) 68(23): 9788-98 
Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Costello CM, Howell K, Cahill E, McBryan J, Konigshoff M, Eickelberg O, Gaine S, Martin F, McLoughlin P. 
In:
Am J Physiol Lung Cell Mol Physiol (2008) 295(2): L272-84 
Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and -3 kinase inhibitors cediranib and vandetanib
Categories:
 
Authors:
Padera TP, Kuo AH, Hoshida T, Liao S, Lobo J, Kozak KR, Fukumura D, Jain RK. 
In:
Mol Cancer Ther (2008) 7(8): 2272-9 
Emilin1 Deficiency Causes Structural and Functional Defects of Lymphatic Vasculature
Categories:
 
Authors:
Carla Danussi, Paola Spessotto, Alessandra Petrucco, Bruna Wassermann, Patrizia Sabatelli, Monica Montesi, Roberto Doliana, Giorgio M. Bressan, and Alfonso Colombatti 
In:
Mol Cell Biol (2008) 28(12): 4026-39 
Hypoxia Increases Breast Cancer Cell–Induced Lymphatic Endothelial Cell Migration
Categories:
 
Authors:
Mikhaylova M, Mori N, Wildes FB, Walczak P, Gimi B, Bhujwalla ZM 
In:
Neoplasia (2008) 10(4): 380-9 
Human Lymphatic Endothelial Cells Express Multiple Functional TLRs
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Pegu A, Qin S, Fallert Junecko BA, Nisato RE, Pepper MS, Reinhart TA 
In:
J Immunol (2008) 1;180(5): 3399-405 
Evidence for annexin II/S100A10 complex and plasmin in mobilization of cytokine activity of human TrpRS
Categories:
Transfection 
Authors:
Kapoor M, Zhou Q, Otero F, Myers CA, Bates A, Belani R, Liu J, Luo JK, Tzima E, Zhang DE, Yang XL, Schimmel P 
In:
J Biol Chem (2008) 283(4): 2070-7 
Dynamic receptor-dependent activation of inducible nitric oxide synthase by ERK-mediated phosphorylation of Ser745
Categories:
Transfection 
Authors:
Zhang Y, Brovkovych V, Brovkovych S, Tan F, Lee BS, Sharma T, Skidgel RA 
In:
J Biol Chem (2007) 282(44): 32453-61 
Inhibition of Inflammatory Lymphangiogenesis by Integrin 5 Blockade
Categories:
Primary Cells and Media 
Authors:
Dietrich T, Onderka J, Bock F, Kruse FE, Vossmeyer D, Stragies R, Zahn G, Cursiefen C 
In:
Am J Pathol (2007) 171(1): 361-72 
Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Reynolds AM, Xia W, Holmes MD, Hodge SJ, Danilov S, Curiel DT, Morrell NW, Reynolds PN 
In:
Am J Physiol Lung Cell Mol Physiol (2007) 292(5): L1182-92 
The scaffolding adapter Gab1 mediates VEGF signaling and is required for endothelial cell migration and capillary formation
Categories:
Transfection 
Authors:
Laramee M, Chabot C, Cloutier M, Stenne R, Holgado-Madruga M, Wong AJ, Royal I 
In:
J Biol Chem (2007) 282(11): 7758-69 
A Role for Type 1 Corticotropin-Releasing Hormone Receptors in Mediating Local Changes in Chronically Inflamed Tissue
Categories:
Transfection 
Authors:
Ralph JA, Zocco D, Bresnihan B, Fitzgerald O, McEvoy AN, Murphy EP 
In:
Am J Pathol (2007) 170(3): 1121-33 
Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cells survival and migration
Categories:
Transfection 
Authors:
Favier B, Alam A, Barron P, Bonnin J, Laboudie P, Fons P, Mandron M, Herault JP, Neufeld G, Savi P, Herbert JM, Bono F 
In:
Blood (2006) 108(4): 1243-50 
Pre-B-cell Colony Enhancing Factor as a Potential Novel Biomarker in Acute Lung Injury
Categories:
Transfection 
Authors:
Ye SQ, Simon BA, Maloney JP, Zambelli-Weiner A, Gao L, Grant A, Easley RB, McVerry BJ, Tuder RM, Standiford T, Brower R, Barnes KC and Garcia JG 
In:
Am J Respir Crit Care Med (2005) 171(4): 361-370 
PV1 Is a Key Structural Component for the Formation of the Stomatal and Fenestral Diaphragms
Categories:
Transfection 
Authors:
Stan RV, Tkachenko E and Niesman IR 
In:
Mol Biol Cell (2004) 15(8): 3615-3630 
Endothelial cell diversity revealed by global expression profiling
Categories:
Primary Cells and Media 
Authors:
Chi JT, Chang HY, Haraldsen G, Jahnsen FL, Troyanskaya OG, Chang DS, Wang Z, Rockson SG, van de Rijn M, Botstein D, Brown PO. 
In:
Proc Natl Acad Sci USA (2003) 100 (19): 10623-8 
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