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What are the size of CD34+ Cells?

When resting, they are about 8-10 microns.

How can Lonzas Human Skeletal Muscle Myoblasts (HSMM) be differentiated to produce desmin? 

Human Skeletal Muscle Myoblasts usually begin to form multinucleated myotubes when the culture reaches 50-70% confluence. Myotubes are formed by the fusion of several to many myoblasts. Addition of differentiation medium, when the culture reaches...

Why do we recommend that MycoZap Reagent 1 treatment must be conducted in media containing a maximum of 5% (v/v) serum? What happens if by mistake a higher serum percentage was used?

As serum is complexing the MycoZap™ Reagent 1 you would decrease the effective concentration and thus inhibit the elimination reaction. If by mistake the elimination was started with higher serum concentration, no elimination took place. The process...

Approximately what size are the Coronary Artery Smooth Muscle Cells (CASMCs)?

Lonza’s R&D estimates that the CASMC’s are around 30 µm in diameter when rounded/in suspension.

What media can the CD14+ Monocytes be cultured in to maintain the monocyte phenotype?

CD14+ Monocytes can be cultured in IMDM + 10% FBS to help maintain the monocyte phenotype. The cells will slowly become adherent but it can take a week to get good adherence. M-CSF (10 ng/ml) will induce a little proliferation and increase adherence....

Where are Lonzas Human Aortic Smooth Muscle Cells (AoSMC) isolated from?

While Lonza’s Human Aortic Smooth Muscle Cells (AoSMC) are isolated from either the ascending or descending aorta, it is usually the ascending aorta that is used. If the heart comes with the aorta, which happens most of the time, then the AoSMC are...

How much data can be stored on the Lucetta® 2 Luminometer AAL-1002

The Lucetta 2 Luminometer has a high data storage capacity with maximum storage of up to 2000 single sample readings.

How many donors are pooled to create the pooled human cells?

Lonza is offering the following primary cells from single donors and from pooled donors:HUVEC (human umbilical vein endothelial cells)NHEK-neo (human epidermal keratinocytes)HMVEC-dNeo (human microvascular endothelial cells, dermal, neonatal)When...

Where are Lonzas Pulmonary Artery Smooth Muscle Cells (PASMC) cells isolated from?

There is no specification on whether the tissue for Lonza’s PASMCs comes from the area closest to the heart or the area closest to the lung.Generally, the tissue is pulled from the area branching off the heart so long as Lonza receives a long enough...

When would be the optimal time to perform experiments post osteogenic differentiation for human mesenchymal stem cells?

Once the cells have differentiated and started laying down bone matrix, we recommend assaying the cells immediately. If cells begin to delaminate (peel of the culture plate in layers), this would indicate that the cells are embedded in the calcium...
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