There is no specification on whether the tissue for Lonza’s PASMCs comes from the area closest to the heart or the area closest to the lung.

Generally, the tissue is pulled from the area branching off the heart so long as Lonza receives a long enough tissue source to properly isolate a sufficient number of cells. Lonza production estimates that 95% of the time, the pulmonary artery that is used for our PASMCs comes directly off the heart. It is rarely, if ever that we get the branched sections located near the lungs.