Seminal fluid enhances replication of human T-cell leukemia virus type 1: implications for sexual transmission

Authors:
Moriuchi M and Moriuchi H
In:
Source: J Virol
Publication Date: (2004)
Issue: 78(22): 12709-12711
Research Area:
Immunotherapy / Hematology
Cells used in publication:
PBMC, human
Species: human
Tissue Origin: blood
Platform:
Nucleofector® I/II/2b
Abstract
Seminal fluid enhanced human T-cell leukemia virus type 1 (HTLV-1) infection by transactivating the HTLV-1 long terminal repeat promoter, which is chromosomally integrated in a cell-type-dependent manner. Our data may indicate a potential role for seminal fluid in the sexual transmission of HTLV-1 and imply complex features of regulation of HTLV-1 expression.
Open in PubMed

Privacy | Legal | About Lonza

© Lonza. All rights reserved.