Dendritic cell, the immunotherapeutic cell for cancer

Nagaraj S, Ziske C and Schmidt-Wolf IGH
Source: Indian J Med Res
Publication Date: (2004)
Issue: 119: 133-138
Cells used in publication:
Dendritic cell (NHDC), human
Species: human
Tissue Origin: blood
Dendritic cells play an important role in the development of effective cancer vaccines. These cells have the potential to present tumour-specific antigens and thereby induce an immune response. Various studies involving clinical trials have investigated the efficacy of administering antigen-loaded dendritic cells for cancer therapy. In order to design such experiments it is important to consider specific antigens, which initiate either a CD4+ or CD8+ response or both. The present review discusses the unique properties of dendritic cells as an immunotherapeutic cell for cancer.