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Co-culture protocol for Keratinocytes and Fibroblasts (2D) 

If you are searching for a 2D co-culture protocol for matched donor Keratinocytes and Fibroblasts, please find our co-culture protocol on Matched Donor Keratinocytes and Fibroblasts 2D Co-Culture ProtocolFurthermore, here is our White Paper...

Where are Lonza’s dermal fibroblasts (NHDF) isolated from?

Lonza’s offers dermal fibroblasts from both adult and neonatal donors. Lonza’s adult dermal fibroblasts (NHDF-Ad) are usually isolated from tissue obtained from elective cosmetic surgical procedures. Generally, these procedures are abdominoplasties...

Where are Lonza’s aortic adventitial fibroblasts (AoAF) isolated from?

Lonza’s aortic adventitial fibroblasts (AoAF) are isolated from the outer connective tissue layer of the aorta. The aortia is divided into three layers. The tunica intima is the inner endothelial layer, the tunica media is the layers of the smooth...

Where are Lonza’s lung fibroblasts (NHLF and DHLF) isolated from?

Lonza’s lung fibroblasts are not taken from any specific area of the lung but instead are taken from an area that appears to be in good shape and is non-hemorrhagic. The pleural membrane is removed and the peripheral tissue is used. Enzymatic...

Where are Lonza’s Ventricular Normal Human Cardiac Fibroblast cells isolated from?

Lonza obtains our Ventricular Normal Human Cardiac Fibroblast (NHCF-V) from left ventricle.

Where are Lonza’s Atrial Normal Human Cardiac Fibroblast cells isolated from?

Lonza obtains our Atrial Normal Human Cardiac Fibroblast (NHCF-A) from right atrium.

Can an alternate to the 5-bromo-2'-deoxyuridine (BrdU) be used to control the growth of fibroblasts when culturing rat cardiac myocytes?

At this time, we can only recommend the use of BrdU for controlling the growth of fibroblasts.When developing this product, we tried using cytosine beta-arabino furanoside (CAF) to inhibit fibroblast growth. While CAF successfully inhibited...

What is the difference between the FBM™ Fibroblast Growth Basal Medium CC-3131 and the SCBM™ Stromal Cell Growth Basal Medium CC-3204? Can the FBM™ Basal Medium and the SCBM™ Basal Medium be used interchangeable? Is there a phenol red free version of the FBM™ Basal Medium?

The FBM™ Basal Medium and the SCBM™ Basal Medium are essentially the same except that the FBM™ Basal Medium contains phenol red and the SCBM™ Basal Medium does not. The FBM™ Basal Medium and the SCBM™ Basal Medium can always be used interchangeably...

Can hydrocortisone be excluded from the Clonetics® BulletKit® when culturing cells? What is the purpose of hydrocortisone in the culture media?

Hydrocortisone is used for at least two purposes in Lonza’s primary cell culture media. Hydrocortisone (in combination with low serum concentrations) will inhibit the takeover of the culture by fibroblasts which may be present in small numbers from...

What is the purpose of the 5-bromo-2'-deoxyuridine (BrdU) when culturing rat cardiac myocytes?

5-bromo-2'-deoxyuridine (BrdU) is very efficient at inhibiting the proliferation of fibroblasts which are natively present at the time of isolation. Without the addition of the BrdU, the fibroblasts would overtake the culture.
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