Search Results

Tight junction disruption by cadmium in an in vitro human airway tissue model

BACKGROUND: The cadmium (Cd) present in air pollutants and cigarette smoke has the potential of causing multiple adverse health outcomes involving damage to pulmonary and cardiovascular tissue. Injury to pulmonary epithelium may include alterations...

Authors: Cao X, Lin H, Muskhelishvili L, Latendresse J, Richter P, Heflich RH

Intramyocardial transplantation of cardiac mesenchymal stem cells reduces myocarditis in a model of chronic Chagas disease cardiomyopathy

INTRODUCTION: New therapeutic options are necessary for patients with chronic Chagas disease, a leading cause of heart failure in Latin American countries. Stem cell therapy focused on improving cardiac function is a promising approach for treating...

Authors: Silva DN, de Freitas Souza BS, Azevedo CM, Vasconcelos JF, Carvalho RH, Soares MB, Dos Santos RR.

Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M

Glucocorticoids are among the most commonly used anti-inflammatory agents. Despite the enormous efforts in elucidating the glucocorticoid-mediated anti-inflammatory actions, how glucocorticoids tightly control overactive inflammatory response is not...

Authors: Miyata M, Lee JY, Susuki-Miyata S, Wang WY, Xu H, Kai H, Kobayashi KS, Flavell RA, Li JD

Spontaneous immortalization of mouse liver sinusoidal endothelial cells.

The spontaneous immortalization of cells in vitro is a rare event requiring genomic instability, such as alterations in chromosomes and mutations in genes. In the present study, we report a spontaneously immortalized liver sinusoidal endothelial cell...

Authors: Zhao X, Zhao Q, Luo Z, Yu Y, Xiao N, Sun X, Cheng L.

SST Peer Reviewed

ON01210.Na (Ex-RADH) Mitigates Radiation Damage through Activation of the AKT Pathway

Development of radio-protective agents that are non-toxic is critical in light of ever increasing threats associated with proliferation of nuclear materials, terrorism and occupational risks associated with medical and space exploration. In this...

Authors: Anthony D. Kang, Stephen C. Cosenza,Marie Bonagura,Manoj Manair,M. V. Ramana Reddy, E. Premkumar...

Directional secretory response of double stranded RNA-induced thymic stromal lymphopoetin (TSLP) and CCL11/eotaxin-1 in human asthmatic airways

BACKGROUND: Thymic stromal lymphoproetin (TSLP) is a cytokine secreted by the airway epithelium in response to respiratory viruses and it is known to promote allergic Th2 responses in asthma. This study investigated whether virally-induced secretion...

Authors: Nino G, Huseni S, Perez GF, Pancham K, Mubeen H, Abbasi A, Wang J, Eng S, Colberg-Poley AM, Pillai...

Mesenchymal stem cell-tumor cell cooperation in breast cancer vasculogenesis

Mesenchymal stem cells (MSCs) are able to acquire endothelial-like characteristics but their involvement in regulating MSC vasculogenesis is more complex. MSCs are able to express endothelial markers when cultured in endothelial growth medium (EGM),...

Authors: SERBAN COMSA, FELICIA CIUCULESCU and MARIUS RAICA

SST Peer Reviewed

Melanocortins Contribute to Sequential Differentiation and Enucleation of Human Erythroblasts via Melanocortin Receptors 1, 2 and 5

In this study, we showed that adrenocorticotropic hormone (ACTH) promoted erythroblast differentiation and increased the enucleation ratio of erythroblasts. Because ACTH was contained in hematopoietic medium as contamination, the ratio decreased by...

Authors: Eriko Simamura1, Tomohiro Arikawa2, Takayuki Ikeda, Hiroki Shimada, Hiroki Shoji, Hiroko Masuta,...

Differentiation of human hair follicle stem cells into endothelial cells induced by vascular endothelial and basic fibroblast growth factors

Hair follicle stem cells (HFSCs) possess powerful expansion and multi-differentiation potential, properties that place them at the forefront of the field of tissue engineering and stem cell-based therapy. The aim of the present study was to...

Authors: ZHI CHENG XU, QUN ZHANG and HONG LI

SST Peer Reviewed

Biomedical Application of Low Molecular Weight Heparin/Protamine Nano/Micro Particles as Cell- and Growth Factor-Carriers and Coating Matrix

Low molecular weight heparin (LMWH)/protamine (P) nano/micro particles (N/MPs) (LMWH/P N/MPs) were applied as carriers for heparin-binding growth factors (GFs) and for adhesive cells including adipose-derived stromal cells (ADSCs) and bone...

Authors: Ishihara M, Kishimoto S, Takikawa M, Hattori H, Nakamura S, Shimizu M.

Data Type

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Platform

Topic

Tight junction disruption by cadmium in an in vitro human airway tissue model

Intramyocardial transplantation of cardiac mesenchymal stem cells reduces myocarditis in a model of chronic Chagas disease cardiomyopathy

Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M

Spontaneous immortalization of mouse liver sinusoidal endothelial cells.

ON01210.Na (Ex-RADH) Mitigates Radiation Damage through Activation of the AKT Pathway

Directional secretory response of double stranded RNA-induced thymic stromal lymphopoetin (TSLP) and CCL11/eotaxin-1 in human asthmatic airways

Mesenchymal stem cell-tumor cell cooperation in breast cancer vasculogenesis

Melanocortins Contribute to Sequential Differentiation and Enucleation of Human Erythroblasts via Melanocortin Receptors 1, 2 and 5

Differentiation of human hair follicle stem cells into endothelial cells induced by vascular endothelial and basic fibroblast growth factors

Biomedical Application of Low Molecular Weight Heparin/Protamine Nano/Micro Particles as Cell- and Growth Factor-Carriers and Coating Matrix