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How can cells be cured of mycoplasma contamination?

Where contamination has occurred, and the sample absolutely cannot be discarded, the MycoZap™ Mycoplasma Elimination Reagent has been optimized to eliminate mycoplasma with minimal toxic effects on the cells. The MycoZap™ Reagent eliminates...
Missing: stable lines

How can cells be cured of mycoplasma contamination?

Where contamination has occurred, and the sample absolutely cannot be discarded, the MycoZap™ Mycoplasma Elimination Reagent has been optimized to eliminate mycoplasma with minimal toxic effects on the cells.The MycoZap™ Reagent eliminates...
Missing: stable lines

Do Lonza's NK cells proliferate in culture?

Publications indicate that IL-2 and IL-21 can stimulate NK cell proliferation in addition to using a human serum supplemented medium.
Missing: stable lines

What are useful methods to enrich/purify specific hematopoetic cell populations before Nucleofection™?

Specific blood cell populations can be enriched/purified for Nucleofection™ by MACS™ selection Kits (Miltenyi Biotec GmbH), RosetteSep™ Kits (StemCell Technologies Inc.) or Dynal™ beads (Invitrogen Corporation).
Missing: stable lines

How do I cryopreserve Lonza’s primary cells? What media cocktail are Lonza’s primary cells cryopreserved in?

Please be aware that cryopreservation may compromise cell quality and performance. Lonza CANNOT guarantee performance of Clonetics™ & Poietics™ Cells that have been cryopreserved outside of Lonza. To avoid loss of cells and forfeiture of your...
Missing: stable lines

I want to stimulate Human T cells post Nucleofection®. Are there any precautions to keep in mind?

After Nucleofection®, wait at least four hours before stimulation. Stimulating immediately after Nucleofection® may lead to increased cell mortality and poor activation of cells. For more details on the stimulation of Human T cells post...
Missing: stable lines

Why do you have different Optimized Protocols for the Nucleofection® of unstimulated and stimulated Human T cells?

We found that the stimulation of T cells not only changes the cells' function but also significantly alters the requirements for successful Nucleofection®. That's why Lonza developed two Optimized Protocols for transfection giving different...
Missing: stable lines

Where are Lonza’s HRE Human Renal Epithelial cells CC-2556 isolated from?

Lonza’s Human Renal Epithelial (HRE) cells are an expansion of HNK (human neonatal kidney) cells. The kidneys are homogenized and the mixed population of cells are cultured in Lonza REGM™ Renal Epithelial Cell Growth Medium for one passage prior...
Missing: stable lines

Why is the morphology of Lonza’s lung microvascular endothelial cells (HMVEC-L) CC-2527 different from most other endothelial cells?

While most endothelial cells will have a “paving stone” type morphology, Lonza’s lung microvascular endothelial cells (HMVEC-L) will generally appear more stretched and elongated, especially at low confluence. This is a normal morphological...
Missing: stable lines

If I use Miltenyi paramagnetic beads for positive selection of cells, i.e. beads remain on the cell surface, does that influence Nucleofection® results?

No, it seems that the beads bound to the cell surface do not have any influence on Nucleofection®. Larger magnetic beads (i.e. > 1µm) may disturb the Nucleofection® process and negatively influence cell viability and efficiency.
Missing: stable lines
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