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CARDIOMYOGENIC DIFFERENTIATION OF FETAL DERIVED MESENCHYMAL STEM CELLS: A TRANSFORMATIVE APPROACH FOR CARDIAC TREATMENT

Authors: Shraddha Singh Gautam; Jaianand Kannaiyan

Therapeutic Benefit of Bone Marrow–Derived Endothelial Progenitor Cell Transplantation after Experimental Aneurysm Embolization with Coil in Rats

Aneurysm embolization with coil is now widely used clinically. However, the recurrence of aneurysms after embolization has always plagued neurosurgeons because the endothelial layer of the aneurysm neck loses its integrity after being embolized by...

Authors: Zhang S, An Q, Li Q, Huang J, Chen X, Chen X, Zhang J, Wang Y, Yang GY, Zhu W.

Critical role of the a1-Na+, K +-ATPase subunit in insensitivity of rodent cells to cytotoxic action of ouabain.

In rodents, ubiquitous a1-Na+, K+-ATPase is inhibited by ouabain and other cardiotonic steroids (CTS) at ~103-fold higher concentrations than those effective in other mammals. To examine the specific roles of the CTS-sensitive a1S- and CTS-resistant...

Authors: Akimova OA, Tverskoi AM, Smolyaninova LV, Mongin AA, Lopina OD, La J, Dulin NO, Orlov SN

SST Peer Reviewed

Diffuse, non-polar electropermeabilization and reduced propidium uptake distinguish the effect of nanosecond electric pulses.

Ca2+ activation and membrane electroporation by 10-ns and 4-ms electric pulses (nsEP and msEP) were compared in rat embryonic cardiomyocytes. The lowest electric field which triggered Ca2+ transients was expectedly higher for nsEP (36kV/cm) than for...

Authors: Semenov I, Zemlin C, Pakhomova ON, Xiao S, Pakhomov AG

SST Peer Reviewed

Mesenchymal stem cell-tumor cell cooperation in breast cancer vasculogenesis.

Mesenchymal stem cells (MSCs) are able to acquire endothelial-like characteristics but their involvement in regulating MSC vasculogenesis is more complex. MSCs are able to express endothelial markers when cultured in endothelial growth medium (EGM),...

Authors: Comsa S, Ciuculescu F, Raica M.

Superior Potential of CD34-Positive Cells Compared to Total Mononuclear Cells for Healing of Nonunion Following Bone Fracture.

We recently demonstrated that the local transplantation of human peripheral blood (PB) CD34+ cells, an endothelial/hematopoietic progenitor cell rich population, contributes to fracture repair via vasculogenesis/angiogenesis and osteogenesis. Human...

Authors: Fukui T, Mifune Y, Matsumoto T, Shoji T, Kawakami Y, Kawamoto A, Ii M, Akimaru H, Kuroda T, Horii M,...

SST Peer Reviewed

Establishing criteria for human mesenchymal stem cell potency.

This study sought to identify critical determinants of mesenchymal stem cell (MSC) potency using in vitro and in vivo attributes of cells isolated from the bone marrow of age- and sex-matched donors. Adherence to plastic was not indicative of...

Authors: Samsonraj RM, Rai B, Sathiyanathan P, Puan KJ, Rötzschke O, Hui JH, Raghunath M, Stanton LW,...

SST Peer Reviewed

Isolation of prostate tumor initiating cells (TICs) through their dielectrophoretic signature.

In this study, the dielectrophoretic response of prostate tumor initiating cells (TICs) was investigated in a microfluidic system utilizing contactless dielectrophoresis (cDEP). The dielectrophoretic response of prostate TICs was observed to be...

Authors: Salmanzadeh A, Romero L, Shafiee H, Gallo-Villanueva RC, Stremler MA, Cramer SD, Davalos RV.

The kinesin KIF21B participates in the cell surface delivery of ?2 subunit-containing GABAA receptors.

KIF21B, a kinesin family (KIF) protein, is a plus end-directed microtubule motor. The KIF21B gene is highly expressed in neuronal tissue and spleen and is a susceptibility locus for multiple sclerosis. KIF21B motility is regulated through TRIM3, a...

Authors: Labonté D, Thies E, Kneussel M.

Advanced Glycation End Products Promote Pro-Atherogenic Changes in Cholesterol Transport: A Possible Mechanism for Cardiovascular Risk in Diabetes

Hyperglycemia is the major cause of diabetic vascular complications. Advanced glycation end products (AGEs) accumulate under hyperglycemic conditions and contribute to atherosclerosis. ATP binding cassette transporters (ABC) A1, ABCG1, and...

Authors: Voloshyna I, Gamez-Godoy J, Littlefield MJ, De Leon J, Castro-Magana M, Reiss AB

SST Peer Reviewed

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CARDIOMYOGENIC DIFFERENTIATION OF FETAL DERIVED MESENCHYMAL STEM CELLS: A TRANSFORMATIVE APPROACH FOR CARDIAC TREATMENT

Therapeutic Benefit of Bone Marrow–Derived Endothelial Progenitor Cell Transplantation after Experimental Aneurysm Embolization with Coil in Rats

Critical role of the a1-Na+, K +-ATPase subunit in insensitivity of rodent cells to cytotoxic action of ouabain.

Diffuse, non-polar electropermeabilization and reduced propidium uptake distinguish the effect of nanosecond electric pulses.

Mesenchymal stem cell-tumor cell cooperation in breast cancer vasculogenesis.

Superior Potential of CD34-Positive Cells Compared to Total Mononuclear Cells for Healing of Nonunion Following Bone Fracture.

Establishing criteria for human mesenchymal stem cell potency.

Isolation of prostate tumor initiating cells (TICs) through their dielectrophoretic signature.

The kinesin KIF21B participates in the cell surface delivery of ?2 subunit-containing GABAA receptors.

Advanced Glycation End Products Promote Pro-Atherogenic Changes in Cholesterol Transport: A Possible Mechanism for Cardiovascular Risk in Diabetes