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6400 results sorted by

Occupational exposure to airborne microorganisms, endotoxins and ß-glucans in poultry houses at different stages of the production cycle.

The aim of the presented study was to assess the exposure of poultry workers to airborne microorganisms, endotoxins and ß-glucans during different stages of the chicken production cycle in 3 commercially-operated poultry houses. Personal and...
Authors: Lawniczek-Walczyk A1, Górny RL, Golofit-Szymczak M, Niesler A, Wlazlo A.

Endotoxin neutralization as a biomonitor for inflammatory bowel disease.

Gram-negative bacterial endotoxin is a potent immunostimulant implicated in the development and/or progression of a variety of diseases. The mammalian immune system has both innate and adaptive immune responses to neutralize endotoxin. In this study,...
Authors: Champion K1, Chiu L, Ferbas J, Pepe M.

Adaptive mutations in the genomes of enterovirus 71 strains following infection of mouse cells expressing human P-selectin glycoprotein ligand-1.

We recently identified human P-selectin glycoprotein ligand-1 (PSGL-1) as a functional enterovirus 71 (EV71) receptor and demonstrated PSGL-1-dependent replication for some EV71 strains in human leukocytes. Here, we report that four out of five...
Authors: Miyamura K, Nishimura Y, Abo M, Wakita T, Shimizu H
SST Peer Reviewed

The effect of transcatheter injections on cell viability and cytokine release of mononuclear cells.

BACKGROUND AND PURPOSE: Several studies suggest that various types of cellular therapies enhance recovery after stroke in animal models. IA-based delivery of cells to the brain is under investigation for stroke, but it is unknown whether cells are...
Authors: El Khoury R, Misra V, Sharma S, Cox CS, Walker P, Grotta JC, Gee A, Suzuki S, Savitz SI.
SST Peer Reviewed

Measurement of endotoxins in bioaerosols at workplace: a critical review of literature and a standardization issue.

Endotoxins are lipopolysaccharides found in the outer membrane of most Gram-negative bacteria and cyanobacteria. Worker exposure to endotoxins has been shown in a number of work situations and is associated with both respiratory and systemic...
Authors: Duquenne P1, Marchand G, Duchaine C.

Dietary oil composition differentially modulates intestinal endotoxin transport and postprandial endotoxemia.

BACKGROUND: Intestinal derived endotoxin and the subsequent endotoxemia can be considered major predisposing factors for diseases such as atherosclerosis, sepsis, obesity and diabetes. Dietary fat has been shown to increase postprandial...
Authors: Mani V1, Hollis JH, Gabler NK.

In vitro anti-proliferative and anti-angiogenic activities of thalidomide dithiocarbamate analogs

Inhibition of angiogenesis is currently perceived as a promising strategy in the treatment of cancer. The anti-angiogenicity of thalidomide has inspired a second wave of research on this teratogenic drug. The present study aimed to investigate the...
Authors: El-Aarag BY, Kasai T, Zahran MA, Zakhary NI, Shigehiro T, Sekhar SC, Agwa HS, Mizutani A, Murakami...

Recombinant factor C (rFC) assay and gas chromatography/mass spectrometry (GC/MS) analysis of endotoxin variability in four agricultural dusts.

Endotoxin exposure is a significant concern in agricultural environments due to relatively high exposure levels. The goals of this study were to determine patterns of 3-hydroxy fatty acid (3-OHFA) distribution in dusts from four types of agricultural...
Authors: Saito R1, Cranmer BK, Tessari JD, Larsson L, Mehaffy JM, Keefe TJ, Reynolds SJ.

PKCd is required for Jagged-1 induction of human mesenchymal stem cell osteogenic differentiation.

JAG1, the gene for the Jagged-1 ligand (Jag1) in the Notch signaling pathway, is variably mutated in Alagille Syndrome (ALGS). ALGS patients have skeletal defects, and additionally JAG1 has been shown to be associated with low bone mass through...
Authors: Zhu F, Sweetwyne MT, Hankenson KD.
SST Peer Reviewed

NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class I specificities.

This study exploited alloreactivity of natural killer (NK) cells for augmenting the recognition of human acute myeloid leukemia (AML). To circumvent the inhibitory effect of killer immunoglobulin receptor (KIR) signaling, we generated NK-cell lines...
Authors: Diermayr S, Himmelreich H, Durovic B, Mathys-Schneeberger A, Siegler U, Langenkamp U, Hofsteenge J,...
SST Peer Reviewed
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