Search Results

Airborne microorganisms, endotoxin, and dust concentration in wood factories in Italy.

Exposure to biological agents and dusts occurs in homes and occupational environments and it is known to cause adverse health effects. There is limited information concerning the occupational exposure levels of airborne biohazard during wood...

Authors: Gioffrè A1, Marramao A, Iannò A.

Influence of the apical enlargement size on the endotoxin level reduction of dental root canals.

Gram-negative bacteria play an essential role in endodontic infections because they have virulence factors such as endotoxin. Due to its potential cytotoxic activity, special attention has been given to the removal/neutralization of this endotoxin in...

Authors: Marinho AC1, Martinho FC, Zaia AA, Ferraz CC, Gomes BP.

Robust inducible Cre recombinase activity in the human malaria parasite Plasmodium falciparum enables efficient gene deletion within a single asexual erythrocytic growth cycle.

Asexual blood stages of the malaria parasite, which cause all the pathology associated with malaria, can readily be genetically modified by homologous recombination, enabling the functional study of parasite genes that are not essential in this part...

Authors: Collins CR1, Das S, Wong EH, Andenmatten N, Stallmach R, Hackett F, Herman JP, Müller S, Meissner M,...

SST Peer Reviewed

Gene expression profile of patients with Mayer-Rokitansky-Küster-Hauser syndrome: new insights into the potential role of developmental pathways

Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) is a rare disease characterized by congenital aplasia of uterus and vagina. Although many studies have investigated several candidate genes, up to now none of them seem to be responsible for the...

Authors: Nodale C, Ceccarelli S, Giuliano M, Cammarota M, D\\\'Amici S, Vescarelli E1, Maffucci D3, Bellati...

Evidence for endotoxin contamination in plastic Na+-heparin blood collection tube lots.

BACKGROUND: Biomarker assays are often conducted on whole blood samples in the course of drug development studies. Because bacterial lipopolysaccharide (LPS) (endotoxin) contamination is known to cause spontaneous cytokine production by monocytes,...

Authors: Newhall KJ1, Diemer GS, Leshinsky N, Kerkof K, Chute HT, Russell CB, Rees W, Welcher AA, Patterson...

Characterization of Human Vaginal Mucosa Cells for Autologous In Vitro Cultured Vaginal Tissue Transplantation in Patients with MRKH Syndrome

Mayer-Rokitansky-Küster-Hauser (MRKH) is a rare syndrome characterized by congenital aplasia of the uterus and vagina. The most common procedure used for surgical reconstruction of the neovagina is the McIndoe vaginoplasty, which consists in creation...

Authors: Nodale C1, Vescarelli E1, D\\\'Amici S1, Maffucci D2, Ceccarelli S1, Monti M2, Benedetti Panici P2,...

Adaptation of the genetically tractable malaria pathogen Plasmodium knowlesi to continuous culture in human erythrocytes.

Research into the aetiological agent of the most widespread form of severe malaria, Plasmodium falciparum, has benefitted enormously from the ability to culture and genetically manipulate blood-stage forms of the parasite in vitro. However, most...

Authors: Moon RW1, Hall J, Rangkuti F, Ho YS, Almond N, Mitchell GH, Pain A, Holder AA, Blackman MJ.

SST Peer Reviewed

Occupational exposure to airborne microorganisms, endotoxins and ß-glucans in poultry houses at different stages of the production cycle.

The aim of the presented study was to assess the exposure of poultry workers to airborne microorganisms, endotoxins and ß-glucans during different stages of the chicken production cycle in 3 commercially-operated poultry houses. Personal and...

Authors: Lawniczek-Walczyk A1, Górny RL, Golofit-Szymczak M, Niesler A, Wlazlo A.

A role for parasite-induced PGE2 in IL-10-mediated host immunoregulation by skin stage schistosomula of Schistosoma mansoni

Significant quantities of PGE(2) were produced by cercariae of Schistosoma mansoni following incubation with linoleic acid, a free fatty acid found on the surface of the skin. Cyclooxygenase (COX) 2 inhibitors failed to block this PGE(2) production,...

Authors: Ramaswamy K, Kumar P, He YX.

Transcription factor binding site analysis identifies FOXO transcription factors as regulators of the cutaneous wound healing process

The search for significantly overrepresented and co-occurring transcription factor binding sites in the promoter regions of the most differentially expressed genes in microarray data sets could be a powerful approach for finding key regulators of...

Authors: Roupé KM, Veerla S, Olson J, Stone EL, Sørensen OE, Hedrick SM, Nizet V

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