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I transfected neurons using the 4D-Nucleofector® Y-Unit. After Nucleofection®, there were precipitates in my culture. What can I do?

Most likely there was too much Nucleofector® Solution left before medium addition. Please try to aspirate solution after Nucleofection® as complete as possible without disturbing cell adherence, but add medium quickly to avoid cells...
Missing: stable lines

How does TheraPEAK 293-GT® Media System compare to other AAV production media on the market?

Download our application note or product sheet to see cell growth, cell viability, viral titer and viral capsid data for TheraPEAK 293-GT® Media System as compared to the industry leading complete production kit and the industry leading media...
Missing: stable lines

What is the shelf life of the PyroCell® MAT System Kits?

Except for the pMAT cells, the shelf life of each component is indicated on the vial label or the kit box label. The pMAT cells can be used for up to 6 months as of receiving.PyroCell® MAT System Kits component should be used beyond its expiry...
Missing: stable lines

What media can the CD14+ Monocytes be cultured in to maintain the monocyte phenotype?

CD14+ Monocytes can be cultured in IMDM + 10% FBS to help maintain the monocyte phenotype. The cells will slowly become adherent but it can take a week to get good adherence. M-CSF (10 ng/ml) will induce a little proliferation and increase adherence...
Missing: stable lines

Why does Lonza recommend two different concentrations of the B-Glycerophosphate in the Normal Human Osteoblasts (NHOst) differentiation protocol?

Lonza R&D has found some NHOst cell strains to be more sensitive to B-Glycerophosphate than others. While it is necessary to differentiate, at too high of concentrations the cells will lift off dish, curl up and die. As such, Lonza recommends...
Missing: stable lines

What is the difference between the EGM™ and EGM™-2 growth media? What is the difference between the EGM™-MV and EGM™-2MV growth media?

...and epidermal growth factor (hEGF).Cells tend to proliferate better in the EGM™-2 and EGM™-2MV growth media versions, however some customers have indicated that the original EGM™ and EGM™MV growth media works better for VEGF, FGF and angiogenesis research...
Missing: stable lines

When is the ideal time to study Lonza’s Human Knee Articular Chondrocytes (NHAC-kn) after re-differentiation?

...will result in the cells losing their differentiated phenotype until the culture is almost 100% de-differentiated and no longer express collagen. For optimal re-differentiation, cells should be expanded as few times as necessary prior to re-differentiation....
Missing: stable lines

Why must Lonza’s Normal Human Articular Chondrocytes (NHAC-kn) be re-differentiated to express collagen?

Lonza’s Normal Human Articular Chondrocytes (NHAC-kn) are differentiated cells which express collagen when they are initially isolated, however, they lose their differentiated phenotype after serial expansion in monolayer culture so that by the 2nd...
Missing: stable lines

Does the MycoAlert® Assay recognize the whole spectrum of mycoplasma?

The mycoplasma specific metabolism detected by the MycoAlert® Assay is present in all members of the mollicute family (Mycoplasma, Acholeplasma, Entomoplasma and Spiroplasma) except Ureaplasma (which are no usual suspects in cell culture). 95...
Missing: stable lines

Why do I need endotoxin-free materials to conduct the PyroCell® Monocyte Activation Test (MAT)?

...should be prepared with materials that do not contain assayable levels of endotoxin which means that endotoxin contents are below the detection limit of the MAT assay.In addition, the cell culture step must be prepared aseptically using sterile...
Missing: stable lines
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