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I see activation of my monocytes (or macrophages or DCs) following Nucleofection®. Why is this? What can I do to address this problem?

We have examined the effects of Nucleofection® (without DNA) on these cells and have not observed significant activation. This indicates that neither the Nucleofector® Solution, the Nucleofector® Program nor the recovery medium...
Missing: stable lines

What is the basic principle of the Nucleofector® Technology?

The Nucleofector® Technology is a novel transfection method especially designed for the needs of primary cells and difficult-to-transfect cell lines. It is a non-viral method based on a unique combination of electrical parameters and cell...
Missing: stable

Can I use the Nucleofector® 2b Solutions and Optimized Protocols with the 4D-Nucleofector® X-Unit or the 96-well Shuttle® System?

No. The 4D-Nucleofector and 96-well Shuttle® System uses specifically optimized electrical parameters and solutions. Five different 4D-Nucleofector or 96-well Shuttle® Solutions are available for primary cells. For cell lines, three...
Missing: stable

What is the proof that DNA enters the nucleus during Nucleofection®?

...is a prerequisite for DNA entry into the nucleus. Until now, the only method to transfect non-dividing cells was by using a viral vector system. 2.) In nucleofected cells gene expression can be detected shortly after Nucleofection®. In cell lines, the transfected...
Missing: stable

Do we sell the Nucleofector® Solution (or any other component of the Nucleofector® Kit) separately?

We don't sell the individual components of the kits separately because our product line is a kit concept line to ensure the use of certified products with quality controlled lot numbers that guarantee optimal results.
Missing: stable cell

Pathogenic human coronaviruses such as severe acute respiratory syndrome CoV (SARS-CoV) predominantly infect lower airways and can cause fatal pneumonia. What kind of products you have to support this research area?

SARS-Cov-2 enters target cells through the (angiotensin converting enzyme) - receptor leading to infections of ACE-2 expressing target cells1 . ACE2 is an important regulator of the immune response and inflammation. It is expressed...
Missing: stable lines

What are the difference between the KGM®, KGM®-2, KGM-Gold® BulletKit®?

...is trying to reproduce a scholarly article where KGM® Medium or KGM®-2 Medium was used with either a cell line, cells they isolated on their own, or cells from another source.On the below datasheet, you can see the supplements included in each...
Missing: stable

How do you ship the PyroCell® Monocyte Activation Test (MAT) Kits?

Depending on the scheduled transfer time, cryopreserved goods are either transported in a styrofoam box with dry ice, or in the vapor phase of liquid nitrogen (LN). Upon receiving, ensure immediate storage of components at = -80°C.If dry...
Missing: stable lines

Where do I find information on the CytoSMART™ System?

Lonza has discontinued to sell the CytoSMART™ System. CytoSMART Technologies has taken over sole support of CytoSMART™ 2 and CytoSMART™ Lux 10X Units.For technical and other questions, please contact CytoSMART Technologies’ support board. More...
Missing: stable lines

What is the difference between each of the types of HUVECs that Lonza offers?

When choosing between the various types of HUVECs that Lonza offers, the choice can be made by answering the following questions:What media do you intend to culture the cells in?Do you require pooled or single donor cells?Do you require additional...
Missing: stable lines
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