Search Results

PyroTec Pro: How long does the assay take, and can an assay be run overnight?

Typical runtime from start of the automated microplate setup to completion of WinKQCL™ Software reading the plate for a single assay is 1.5 hours – 2.5 hours, depending on the number of samples and the complexity of the dilutions. Therefore, a...

Are all of the PyroTec Pro consumables endotoxin-free?

All consumables, including pipette tips (P/N 0000229884), troughs (P/N 0000229888), 13 x 100 mm tubes (P/N N207), and microplates (P/N 25-340) used in the system are certified to be endotoxin-free (<0.005 EU/mL).

How long does it take to perform the PyroTec Pro installation, operational and performance (IOPQ)?

There are many components that need to be installed and validated. Depending on the customizations needed, estimated time for installation and operational qualification is one week.

How are PyroTec™ Pro manual steps controlled by WinKQCL software?

Pop-up windows in the WinKQCL™ Software application guide the user through manual preparation (endotoxin, reagents, sample), and every step has to be actively confirmed by the user, which acts as a fail-safe. For data integrity purposes, it reduces...

Can PyroTec Pro automated systems share the same WinKQCL™ Software database for trending and data security?

Yes, the system is able to leverage the robust enterprise features of the WinKQCL™ Software. This includes storing all information in a WinKQCL™ Software database that can be shared amongst the organization with fine-grain user access controls and...

Can plate dilutions schemes be transferred to WinKQCL™ Software if contained in a LIMS?

Yes, this information can be pulled from a LIMS if available. For example, an export created in CSV can be exported back into LIMS.

Is it possible to automate the PyroTec Pro standard dilutions?

The standard endotoxin dilutions are created by the system based on what is specified in the WinKQCL™ Software Template specific for that assay. The PyroTec™ PRO System can dynamically create the dilution scheme in the WinKQCL™ Software.The system...

Does the reported Log4j vulnerability threat affect our WinKQCL software (Catalog # 25-611E)?

Thank you for using Lonza Endotoxin Detection Products.Lonza has been providing endotoxin detection products and services since the 1970s, leading the way in innovation of products, methods and software.Our dedicated WinKQCL software is on the market...

The effect of chitin size, shape, source and purification method on immune recognition.

The animal immune response to chitin is not well understood and needs to be investigated further. However, this is a challenging topic to study because of the technical difficulties in purifying chitin, and because this material usually comes...

Authors: Alvarez FJ.

Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation.

Chitin is an essential structural polysaccharide of fungal pathogens and parasites, but its role in human immune responses remains largely unknown. It is the second most abundant polysaccharide in nature after cellulose and its derivatives today are...

Authors: Wagener J1, Malireddi RK2, Lenardon MD1, Köberle M3, Vautier S1, MacCallum DM1, Biedermann T3,...

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