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Can PyroTec Pro automated systems share the same WinKQCL™ Software database for trending and data security?

Yes, the system is able to leverage the robust enterprise features of the WinKQCL™ Software. This includes storing all information in a WinKQCL™ Software database that can be shared amongst the organization with fine-grain user access controls and...

Can plate dilutions schemes be transferred to WinKQCL™ Software if contained in a LIMS?

Yes, this information can be pulled from a LIMS if available. For example, an export created in CSV can be exported back into LIMS.

Is it possible to automate the PyroTec Pro standard dilutions?

The standard endotoxin dilutions are created by the system based on what is specified in the WinKQCL™ Software Template specific for that assay. The PyroTec™ PRO System can dynamically create the dilution scheme in the WinKQCL™ Software.The system...

Does the reported Log4j vulnerability threat affect our WinKQCL software (Catalog # 25-611E)?

Thank you for using Lonza Endotoxin Detection Products.Lonza has been providing endotoxin detection products and services since the 1970s, leading the way in innovation of products, methods and software.Our dedicated WinKQCL software is on the market...

The effect of chitin size, shape, source and purification method on immune recognition.

The animal immune response to chitin is not well understood and needs to be investigated further. However, this is a challenging topic to study because of the technical difficulties in purifying chitin, and because this material usually comes...

Authors: Alvarez FJ.

Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation.

Chitin is an essential structural polysaccharide of fungal pathogens and parasites, but its role in human immune responses remains largely unknown. It is the second most abundant polysaccharide in nature after cellulose and its derivatives today are...

Authors: Wagener J1, Malireddi RK2, Lenardon MD1, Köberle M3, Vautier S1, MacCallum DM1, Biedermann T3,...

Endotoxin-induced monocytic microparticles have contrasting effects on endothelial inflammatory responses.

Septic shock is a severe disease state characterised by the body's life threatening response to infection. Complex interactions between endothelial cells and circulating monocytes are responsible for microvasculature dysfunction contributing to the...

Authors: Wen B, Combes V, Bonhoure A, Weksler BB, Couraud PO, Grau GE.

Human endothelial cell-based assay for endotoxin as sensitive as the conventional Limulus Amebocyte Lysate assay

Endotoxin, also known as lipopolysaccharide (LPS) produced by bacteria can be present in any liquid or on any biomaterial even if the material is sterile. Endotoxin in mammals can cause fever, inflammation, cell and tissue damage and irreversible...

Authors: Unger RE, Peters K, Sartoris A, Freese C, Kirkpatrick CJ

Analysis of wear, wear particles, and reduced inflammatory potential of vitamin E ultrahigh-molecular-weight polyethylene for use in total joint replacement.

Vitamin E (VE) has been added to ultrahigh-molecular-weight polyethylene (UHMWPE) acetabular cups and tibial trays primarily to reduce oxidative damage to the polymer. The aim of this study was to investigate the relative wear rates of...

Authors: Bladen CL1, Teramura S, Russell SL, Fujiwara K, Fisher J, Ingham E, Tomita N, Tipper JL.

HBD3 regulates matrix metalloproteinase production in human myeloid dendritic cells exposed to Porphyromonas gingivalis hemagglutinin B

Matrix metalloproteinases (MMP) are zinc- or calcium-dependent proteinases involved in the normal maintenance of the extracellular matrix. When elevated, MMPs degrade matrix components contributing to tissue destruction in infected periodontal sites....

Authors: Raina M

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