media

Hematopoietic Progenitor Growth Medium

HPGM is a serum-free medium containing only human proteins that supports the proliferation of hematopoietic progenitor with the addition of cytokines.

Please note: HPGM is being discontinued. In its place we recommend one of the X-Vivo Cell Culture Media varieties.

Shelf Life:

6 months

Recommended for Cells:

CD34+ cell, human ; CD133+, human ; Erythroid progen., cord blood, human

Categories:

Primary Cells and Media

Research Areas:

Immunotherapy / Hematology

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Citations (26)

Reprogramming fibroblasts toward cardiomyocytes, neural stem cells and hepatocytes by cell activation and signaling-directed lineage conversion

Categories:

Transfection

Authors:

Saiyong Zhu, Haixia Wang, Sheng Ding

In:

Nat Protocols (2015) 10 (7): 959-73

Biomedical Application of Low Molecular Weight Heparin/Protamine Nano/Micro Particles as Cell- and Growth Factor-Carriers and Coating Matrix

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Ishihara M, Kishimoto S, Takikawa M, Hattori H, Nakamura S, Shimizu M.

In:

Int J Mol Sci (2015) 15: 11785-803

Melanocortins Contribute to Sequential Differentiation and Enucleation of Human Erythroblasts via Melanocortin Receptors 1, 2 and 5

Categories:

Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Eriko Simamura1, Tomohiro Arikawa2, Takayuki Ikeda, Hiroki Shimada, Hiroki Shoji, Hiroko Masuta, Yuriko Nakajima, Hiroki Otani, Hideto Yonekura, Toshihisa Hatta

In:

PLoS ONE (2015) 10: e0123232

UMG Lenti: novel lentiviral vectors for efficient transgene- and reporter gene expression in human early hematopoietic progenitors.

Categories:

Primary Cells and Media, Serum-free and Speciality Media

Authors:

Chiarella E, Carrà G, Scicchitano S, Codispoti B, Mega T, Lupia M, Pelaggi D, Marafioti MG, Aloisio A, Giordano M, Nappo G, Spoleti CB, Grillone T, Giovannone ED, Spina R, Bernaudo F, Moore MA, Bond HM, Mesuraca M, Morrone G

In:

PLoS ONE (2014) 9(12): ePub

ELMO1 Is Upregulated in AML CD34+ Stem/Progenitor Cells, Mediates Chemotaxis and Predicts Poor Prognosis in Normal Karyotype AML

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Capala ME, Vellenga E, Schuringa JJ

In:

PLoS ONE (2014) 10: e111568

Convergence of hypoxia and TGFß pathways on cell cycle regulation in human hematopoietic stem/progenitor cells

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Wierenga AT, Vellenga E, Schuringa JJ

In:

PLoS ONE (2014) 9(3): e93494

Loss of quiescence and impaired function of CD34(+)/CD38(low) cells one year following autologous stem cell transplantation

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Woolthuis CM, Brouwers-Vos AZ, Huls G, de Wolf JT, Schuringa JJ, Vellenga E

In:

Haematologica (2013) 98(12): 1964-71

Myeloblastic cell lines mimic some but not all aspects of human cytomegalovirus experimental latency defined in primary CD34+ cell populations.

Categories:

Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Albright ER1, Kalejta RF

In:

J Virol (2013) 87(17): 9802-12

A survey of ex vivo/in vitro transduction efficiency of mammalian primary cells and cell lines with Nine natural adeno-associated virus (AAV1-9) and one engineered adeno-associated virus serotype.

Categories:

Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Ellis BL, Hirsch ML, Barker JC, Connelly JP, Steininger RJ 3rd, Porteus MH.

In:

Virol J (2013) 10: 74

ON01210.Na (Ex-RADH) Mitigates Radiation Damage through Activation of the AKT Pathway

Categories:

Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Anthony D. Kang, Stephen C. Cosenza,Marie Bonagura,Manoj Manair,M. V. Ramana Reddy, E. Premkumar Reddy

In:

PLoS ONE (2013) 3: e58355

Cellularity and structure of fresh human coronary thrombectomy specimens; presence of cells with markers of progenitor cells

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Jovin IS, Lei L, Huang Y, Hao Z, Curtis JP, Brennan JJ, Remetz MS, Setaro JF, Pfau SE, Howes CJ, Clancy JF, Cabin HS, Cleman MW, Giordano FJ

In:

J Cell Mol Med (2012) 16(12): 3022-7

Selective Expansion of CD34+ Cells from Mouse Bone Marrow Cultured on LH/P MP-Coated Plates with Adequate Cytokines

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Kishimoto S, Ishihara M, Kanatani Y, Nambu M, Takikawa M, Sumi Y, Nakamura S, Mori Y, Hattori H, Tanaka Y, Sato T

In:

J Tissue Eng. (2011) 2(1): 2041731411425419

The matricellular protein cysteine-rich protein 61 (CCN1/Cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathy

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Hasan A, Pokeza N, Shaw L, Lee HS, Lazzaro D, Chintala H, Rosenbaum D, Grant MB, Chaqour B

In:

J Biol Chem (2011) 286(11): 9542-54

CD34+CD140b+ cells and circulating CXCL12 correlate with the angiographically assessed severity of cardiac allograft vasculopathy

Categories:

Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Schober A, Hristov M, Kofler S, Forbrig R, Löhr B, Heussen N, Zhe Z, Akhtar S, Schumann U, Krötz F, Leibig M, König A, Kaczmarek I, Reichart B, Klauss V, Weber C, Sohn HY

In:

Other (2011) 32(4): 476-84

KRAS(G12V) enhances proliferation and initiates myelomonocytic differentiation in human stem/progenitor cells via intrinsic and extrinsic pathways

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Fatrai S, van Gosliga D, Han L, Daenen SM, Vellenga E, Schuringa JJ

In:

J Biol Chem (2011) 286(8): 6061-70

The role of STAT5 and KRAS in hematopoiesis and acute myeoloid leukemia

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Fátrai S

In:

Other (2010) 0:0: Thesis

An in-vitro Adhesion Pattern study of Hematopoietic Stem Cells on Porous Titanium and Bioceramic Scaffolds

Categories:

Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Rajyalakshmi A, Balasubramanian K, Mishra S

In:

Other (2010) 24(2): 116-122

Cellular and viral control over the initial events of human cytomegalovirus experimental latency in CD34+ cells.

Categories:

Primary Cells and Media, Serum-free and Speciality Media, Transfection

Authors:

Saffert RT, Penkert RR, Kalejta RF

In:

J Virol (2010) 84(11): 5594-604

Induction of nitric oxide by erythropoietin is mediated by the common receptor and requires interaction with VEGF receptor 2

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Sautina L, Sautin Y, Beem E, Zhou Z, Schuler A, Brennan J, Zharikov SI, Diao Y, Bungert J, Segal MS

In:

Blood (2010) 115(4): 896-905

Repression of BMI1 in normal and leukemic human CD34(+) cells impairs self-renewal and induces apoptosis

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Rizo A, Olthof S, Han L, Vellenga E, de Haan G, Schuringa JJ

In:

Blood (2009) 114(8): 1498-505

Downregulation of signal transducer and activator of transcription 5 (STAT5) in CD34+ cells promotes megakaryocytic development, whereas activation of STAT5 drives erythropoiesis

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Olthof SG, Fatrai S, Drayer AL, Tyl MR, Vellenga E, Schuringa JJ

In:

Stem Cells (2008) 26(7): 1732-42

Long-term maintenance of human hematopoietic stem/progenitor cells by expression of BMI1

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Rizo A, Dontje B, Vellenga E, de Haan G, Schuringa JJ

In:

Blood (2008) 111(5): 2621-30

Reduced activation of protein kinase B, Rac, and F-actin polymerization contributes to an impairment of stromal cell derived factor-1 induced migration of CD34+ cells from patients with myelodysplasia

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Fuhler GM, Drayer AL, Olthof SG, Schuringa JJ, Coffer PJ, Vellenga E

In:

Blood (2008) 111(1): 359-68

STAT5 is required for long-term maintenance of normal and leukemic human stem/progenitor cells

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Schepers H, van Gosliga D, Wierenga AT, Eggen BJ, Schuringa JJ, Vellenga E

In:

Blood (2007) 110(8): 2880-8

Reintroduction of C/EBPalpha in leukemic CD34+ stem/progenitor cells impairs self-renewal and partially restores myelopoiesis

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Schepers H, Wierenga AT, van Gosliga D, Eggen BJ, Vellenga E, Schuringa JJ

In:

Blood (2007) 110(4): 1317-25

Mammalian target of rapamycin is required for thrombopoietin-induced proliferation of megakaryocyte progenitors

Categories:

Classical Media and Reagents, Serum-free and Speciality Media

Authors:

Drayer AL, Olthof SG, Vellenga E

In:

Stem Cells (2006) 24(1): 105-14

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