Lonza endothelial cell media ending with –MV (such as the EGM™-MV and EGM™-2MV Growth Media) are typically designated for use with microvascular endothelial cells (with some exceptions).

Lonza endothelial cell media not ending with –MV (such as the EGM™ and EGM™-2 Growth Media) are typically designated for use with large vessel endothelial cells (with some exceptions).

The major difference between the microvascular endothelial cell media (EGM™-MV and EGM™-2MV Growth Media) and the large vessel endothelial cell media (EGM™ and EGM™-2 Growth Media) is the concentration of fetal bovine serum. The microvascular endothelial cell media (EGM™-MV and EGM™-2MV Growth Media) will contain fetal bovine serum at a final concentration of 5% whereas the large vessel endothelial cell media (EGM™ and EGM™-2 Growth Media) will contain fetal bovine serum at a final concentration of 2%.

• In summary:

  • EGM™ / EGM™-MV : contain BBE (undefined component).

  • EGM™-2 / EGM™-2MV : use defined growth factors (no BBE).

  • EGM™-Plus : enhanced version of EGM™, optimized for HUVECs, no exogenous VEGF.

  • –MV versions : higher serum concentration (5%) for microvascular cells.

The EGM-MV BulletKit CC-3125 has been discontinued in 2023