Q:

How does Lonza test for quality of the diseased airway cells?

A:

Diseased Bronchial Epithelial Cells are characterized by morphology through serial passage and some are tested for differentiation using B-ALIā„¢ Differentiation protocols, these are tested for TEER levels, ciliogenesis, and mucin production.

Diseased Bronchial Smooth Muscle Cells test positive for alpha-actin & negative for vWF.

Diseased Lung Fibroblasts test negative for vWF andalpha-actin and positive for cytokeratins 18 & 19.


Population doublings of all cells are reported through multiple passages.

Categories:
Primary Cells and Media
Research Areas:
Respiratory Research