Dorsal root ganglion (DRG), mouse

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A collection of neurons associated with the processing of sensory information. Found within the sensory portion of the spinal nerve, just as the nerve exits the spinal foramina.

Cell Type:
Neurons (Ganglia)
Tissue Origin:
brain
Species:
mouse
Research Area:
Neurobiology
Cell Characteristics:
Adherent

Transfection Information

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Citations (17)

Cold-aggravated pain in humans caused by a hyperactive NaV1.9 channel mutant.
Categories:
Transfection 
Authors:
Leipold E, Hanson-Kahn A, Frick M, Gong P, Bernstein JA, Voigt M, Katona I, Oliver Goral R, Altmüller J, Nürnberg P, Weis J, Hübner CA, Heinemann SH, Kurth I. 
In:
Nat Commun. (2015) 8(6): 1-11 
GABA blocks pathological but not acute TRPV1 pain signals.
Categories:
Transfection 
Authors:
Hanack C, Moroni M, Lima WC, Wende H, Kirchner M, Adelfinger L, Schrenk-Siemens K, Tappe-Theodor A, Wetzel C, Kuich PH, Gassmann M, Roggenkamp D, Bettler B, Lewin GR, Selbach M, Siemens J. 
In:
Cell (2015) 160(4): 759-70 
Promotion of neurite outgrowth by fibroblast growth factor receptor 1 overexpression and lysosomal inhibition of receptor degradation in pheochromocytoma cells and adult sensory neurons
Categories:
Transfection 
Authors:
Hausott B, Schlick B, Vallant N, Dorn R, Klimaschewski L 
In:
Neuroscience (2008) 153(2): 461-73 
Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons
Categories:
Transfection 
Authors:
Hudmon A, Choi JS, Tyrrell L, Black JA, Rush AM, Waxman SG, Dib-Hajj SD 
In:
J Neurosci (2008) 28(12): 3190-201 
The ubiquitin ligase Phr1 regulates axon outgrowth through modulation of microtubule dynamics
Categories:
Transfection 
Authors:
Lewcock JW, Genoud N, Lettieri K, Pfaff SL 
In:
Neuron (2007) 56(4): 604-20 
Neurotrophin activation of NFAT-dependent transcription contributes to the regulation of pro-nociceptive genes
Categories:
Transfection 
Authors:
Groth RD, Coicou LG, Mermelstein PG, Seybold VS 
In:
J Neurochem (2007) 102(4): 1162-74 
Nerve growth factor stimulates the concentration of TrkA within lipid rafts and extracellular signal-regulated kinase activation through c-Cbl-associated protein
Categories:
Transfection 
Authors:
Limpert AS, Karlo JC, Landreth GE 
In:
Mol Cell Biol (2007) 27(16): 5686-98 
Inactivation properties of sodium channel Nav1.8 maintain action potential amplitude in small DRG neurons in the context of depolarization
Categories:
Transfection 
Authors:
Harty TP, Waxman SG 
In:
Mol Pain (2007) 3(1): 12 
Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons
Categories:
Transfection 
Authors:
Zhou X, Babu JR, da Silva S, Shu Q, Graef IA, Oliver T, Tomoda T, Tani T, Wooten MW, Wang F 
In:
Proc Natl Acad Sci USA (2007) 104(14): 5842-7 
A stomatin-domain protein essential for touch sensation in the mouse
Categories:
Transfection 
Authors:
Wetzel C, Hu J, Riethmacher D, Benckendorff A, Harder L, Eilers A, Moshourab R, Kozlenkov A, Labuz D, Caspani O, Erdmann B, Machelska H, Heppenstall PA, Lewin GR 
In:
Nature (2007) 445(7124): 206-9 
Impaired axonal regeneration by isolectin B4-binding dorsal root ganglion neurons in vitro
Categories:
Transfection 
Authors:
Leclere PG, Norman E, Groutsi F, Coffin R, Mayer U, Pizzey J, Tonge D 
In:
J Neurosci (2007) 27(5): 1190-9 
Essential Roles for GSK-3s and GSK-3-Primed Substrates in Neurotrophin-Induced and Hippocampal Axon Growth
Categories:
Transfection 
Authors:
Kim WY, Zhou FQ, Zhou J, Yokota Y, Wang YM, Yoshimura T, Kaibuchi K, Woodgett JR, Anton ES, Snider WD 
In:
Neuron (2006) 52(6): 981-96 
Calmodulin regulates current density and frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons
Categories:
Transfection 
Authors:
Choi JS, Hudmon A, Waxman S, Dib-Hajj SD 
In:
J Neurophysiol (2006) 96(1): 97-108 
Neurotrophins support regenerative axon assembly over CSPGs by an ECM-integrin-independent mechanism
Categories:
Transfection 
Authors:
Zhou FQ, Walzer M, Wu YH, Zhou J, Dedhar S, Snider WD 
In:
J Cell Sci (2006) 119(Pt 13): 2787-96 
Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons
Categories:
Transfection 
Authors:
Dib-Hajj SD, Rush AM, Cummins TR, Hisama FM, Novella S, Tyrrell L, Marshall L and Waxman SG 
In:
Brain (2005) 128(Pt 8): 1847-1854 
NGF-induced axon growth is mediated by localized inactivation of GSK-3beta and functions of the microtubule plus end binding protein APC
Categories:
Transfection 
Authors:
Zhou FQ, Zhou J, Dedhar S, Wu YH and Snider WD 
In:
Neuron (2004) 42(6): 897-912 
BPAG1n4 is essential for retrograde axonal transport in sensory neurons
Categories:
Transfection 
Authors:
Liu JJ, Ding J, Kowal AS, Nardine T, Allen E, Delcroix JD, Wu C, Mobley W, Fuchs E and Yang Y 
In:
J Cell Biol (2003) 163(2): 223-229 
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