cells

Hodgkin's lymphoma

Cell Type:

Leukocyte (unspec.)

Tissue Origin:

blood

Species:

human

Research Area:

Cancer Research/Cell Biology

Immunotherapy / Hematology

Cell Characteristics:

Suspension

Transfection Information

Lonza Optimized Protocol
Optimization Guideline

Filter:

The table below shows data for the cell type and Nucleofector™ Platform selected. Those data are either based on Lonza Optimized Protocols or on results shared from customers who performed an optimization based on our guidelines. In case no data are shown for the selected Nucleofector™ Platform, please take a look at our optimization strategy to get further guidance on how to easily determine optimal Nucleofection conditions yourself.

Protocol	Kit	Program	Cells	Efficiency	Viable Cells	Substrate		Format	Platform
	V	T-001	2e6	68%	42%	Plasmid (general)	5 µg	100 µl	I/II/2b

Citations

CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells

Categories:

Transfection

Authors:

Hirsch B, Hummel M, Bentink S, Fouladi F, Spang R, Zollinger R, Stein H, Dürkop H

In:

Am J Pathol (2008) 172(2): 510-20

STAT3 is essential for Hodgkin lymphoma cell proliferation and is a target of tyrphostin AG17 which confers sensitization for apoptosis

Categories:

Transfection

Authors:

Holtick U, Vockerodt M, Pinkert D, Schoof N, Sturzenhofecker B, Kussebi N, Lauber K, Wesselborg S, Loffler D, Horn F, Trumper L and Kube D

In:

Leukemia (2005) 19(6): 936-944

Epigenetic silencing of the immunoglobulin heavy chain gene in classical Hodgkin lymphoma-derived cell lines contributes to the loss of immunoglobulin expression

Categories:

Transfection

Authors:

Ushmorov A, Ritz O, Hummel M, Leithauser F, Moller P, Stein H and Wirth T

In:

Blood (2004) 104(10): 3326-3334

L1236

Transfection Information

Citations