MedB1
Export
human tumor cell line derived from a primary mediastinal large B-cell lymphoma
Cell Type:
B cell
Tissue Origin:
blood
Species:
human
Research Area:
Cancer Research/Cell Biology
Immunotherapy / Hematology
Cell Characteristics:
Suspension
Transfection Information
Lonza Optimized Protocol
Optimization Guideline
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The table below shows data for the cell type and Nucleofector™ Platform selected. Those data are either based on Lonza Optimized Protocols
or on results shared from customers who performed an optimization based on our guidelines. In case no data are shown for the selected Nucleofector™ Platform, please take a look at our
optimization strategy
to get further guidance on how to easily determine optimal Nucleofection conditions yourself.
Protocol
Kit
Program
Cells
Efficiency
Viable Cells
Substrate
Format
Platform
V
T-001
2e6
34%
65%
Plasmid (general)
5 µg
100 µl
I/II/2b
Citations
Target sequence accessibility limits activation-induced cytidine deaminase activity in primary mediastinal B-cell lymphoma
Categories:
Transfection
Authors:
Popov SW, Moldenhauer G, Wotschke B, Brüderlein S, Barth TF, Dorsch K, Ritz O, Möller P, Leithäuser F
In:
Cancer Res (2007) 67(14): 6555-64
Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in MedB-1 mediastinal lymphoma line
Categories:
Transfection
Authors:
Melzner I, Bucur AJ, Bruderlein S, Dorsch K, Hasel C, Barth TF, Leithauser F and Moller P
In:
Blood (2005) 105(6): 2535-2542