cells

Kupffer cells are the resident macrophages in the liver and are part of the first line of defense against bacteria and toxins in the gut. Kupffer cells exhibit typical macrophage morphology and can be activated to produce inflammatory cytokines, growth factors and reactive oxygen species.

Cell Type:

Macrophage

Tissue Origin:

liver

Species:

human

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Research Area:

Toxicology

Cell Characteristics:

Adherent

Transfection Information

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Citations

The role of sinusoidal endothelial cells and TIMP1 in the regulation of fibrosis in a novel human liver 3D NASH model

Categories:

Primary Cells and Media, 3D Cell Culture

Authors:

van Riet, Sander; Julien, Anais; Atanasov, Andrea Nordling, Åsa; Ingelman-Sundberg, Magnus

In:

Hepatology (2024) 8: e0374.

A 3D Human Liver Model of Nonalcoholic Steatohepatitis

Categories:

Primary Cells and Media, 3D Cell Culture

Authors:

Marion Duriez , Agnes Jacquet , Lucile Hoet , Sandrine Roche , Marie-Dominique Bock , Corinne Rocher , Gilles Haussy , Xavier Vigé , Zsolt Bocskei , Tamara Slavnic , Valérie Martin , Jean-Claude Guillemot , Michel Didier , Aimo Kannt , Cécile Orsini , Vincent Mikol , Anne-Céline Le Fèvre

In:

J Clin Transl Hepatol (2020) 8(4): 359-370

Functionality of Primary Hepatic Non-Parenchymal Cells in a 3D Spheroid Model and Contribution to Acetaminophen Hepatotoxicity

Categories:

3D Cell Culture , Bioassay

Authors:

Catherine C Bell , Bhavik Chouhan , Linda C Andersson , Håkan Andersson , James W Dear , Dominic P Williams , Magnus Söderberg

In:

Arch Toxicol (2020) 94: 1251

Kupffer Cell, human

Transfection Information

Citations