Fibroblast line, human DNA-repair defic.
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Human fibroblast cell lines deficient in DNA repair mechanisms (Nucleotide excision repair (NER), base excision repair (BER), Non-homologous end joining (NHEJ) etc.)
Cell Type:
Fibroblast
Tissue Origin:
dermal
Species:
human
Research Area:
Cancer Research/Cell Biology
Cell Characteristics:
Adherent
Transfection Information
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Citations
RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling
Categories:
Transfection
Authors:
Stewart GS, Stankovic T, Byrd PJ, Wechsler T, Miller ES, Huissoon A, Drayson MT, West SC, Elledge SJ, Taylor AM
In:
Proc Natl Acad Sci USA (2007) 104(43): 16910-5