MOLM-13
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Acute Monocytic leukemia cell line established from peripheral blood of an AML patient
Cell Type:
Monocyte
Tissue Origin:
blood
Species:
human
Research Area:
Cancer Research/Cell Biology
Immunotherapy / Hematology
Cell Characteristics:
Suspension
Transfection Information
Lonza Optimized Protocol
Optimization Guideline
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Any Substrate
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The table below shows data for the cell type and Nucleofector™ Platform selected. Those data are either based on Lonza Optimized Protocols
or on results shared from customers who performed an optimization based on our guidelines. In case no data are shown for the selected Nucleofector™ Platform, please take a look at our
optimization strategy
to get further guidance on how to easily determine optimal Nucleofection conditions yourself.
Protocol
Kit
Program
Cells
Efficiency
Viable Cells
Substrate
Format
Platform
SF
EH-100
CRISPR/Cas
100 µl
4D X-Unit
SF
CA-137
2e6
siRNA
2 µM
100 µl
4D X-Unit
Citations
Inhibiting autophagy targets human leukemic stem cells and hypoxic AML blasts by disrupting mitochondrial homeostasis
Categories:
Transfection, Cell Lines and Primary Cancer Cells
Authors:
Dykstra KM, Fay HRS, Massey AC, Yang N, Johnson M, Portwood S, Guzman ML, Wang ES.
In:
Blood (2021) 5(8): 2087-2100
Cotargeting of XPO1 Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Acute Myeloid Leukemia
Categories:
Transfection
Authors:
Brinton LT, Sher S, Williams K, Canfield D, Orwick S, Wasmuth R, Cempre C, Skinner J, Lehman A, Blachly JS, Byrd JC, Lapalombella R.
In:
Cancers (2020) 12(6): 1574
Novel c-CBL and CBL-B ubiquitin ligase mutations in human acute myeloid leukemia
Categories:
Transfection
Authors:
Caligiuri MA, Briesewitz R, Yu J, Wang L, Wei M, Arnoczky KJ, Marburger TB, Wen J, Perrotti D, Bloomfield CD, Whitman SP
In:
Blood (2007) 110(3): 1022-4