Prostate Epithelial Cell Growth Medium

Prostate Epithelial Cell Growth Medium (PrEGM) BulletKit has been specially formulated for the serum-free maintenance and expansion of human prostate epithelial cells.

Shelf Life:
12 months
Recommended for Cells:
Epithelial, prostate (PrEC), human
Categories:
Primary Cells and Media
Research Areas:
Cancer Research/Cell Biology
Basic Research
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Citations (61)

An apoptosis-enhancing drug overcomes platinum resistance in a tumour-initiating subpopulation of ovarian cancer
Categories:
Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Janzen DM, Tiourin E, Salehi JA, Paik DY, Lu J, Pellegrini M, Memarzadeh S. 
In:
Nat Commun. (2015) 6: 7956 
Increased Notch signaling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells
Categories:
Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Oh-Joon Kwon Joseph Valdez, Li Zhang, Boyu Zhang, Xing Wei1, Qingtai Su, Michael M Ittmann Chad J Creighton, and Li Xin 
In:
Other (2015) 5: 4416 
Spatially restricted Hedgehog signaling regulates HGF-induced branching of the adult prostate
Categories:
Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Lim A, Shin K, Zhao C, Kawano S, Beachy PA. 
In:
Nat Cell Biol (2014) 16(12): 1135-45 
In vitro antitumor activity of stellettin B, a triterpene from marine sponge Jaspis stellifera, on human glioblastoma cancer SF295 cells
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Tang SA, Zhou Q, Guo WZ, Qiu Y, Wang R, Jin M, Zhang W, Li K, Yamori T, Dan S, Kong D 
In:
Mar Drugs (2014) 12(7): 4200-13 
Sensitization of radio-resistant prostate cancer cells with a unique cytolethal distending toxin
Categories:
Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Lai CH, Chang CS, Liu HH, Tsai YS, Hsu FM, Yu YL, Lai CK, Gandee L, Pong RC, Hsu HW, Yu L, Saha D, Hsieh JT. 
In:
OncoTarget (2014) 5(14): 5523-34 
Reduced 64Cu uptake and tumor growth inhibition by knockdown of human copper transporter 1 in xenograft mouse model of prostate cancer.
Categories:
Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Cai H, Wu JS, Muzik O, Hsieh JT, Lee RJ, Peng F. 
In:
J Nuc Medicine (2014) 55(4): 622-8 
Association of DSC3 mRNA down-regulation in prostate cancer with promoter hypermethylation and poor prognosis
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Pan J1, Chen Y1, Mo C1, Wang D1, Chen J1, Mao X1, Guo S2, Zhuang J1, Qiu S1. 
In:
PLoS ONE (2014) 9(3): e92815 
Rosemary (Rosmarinus officinalis) extract modulates CHOP/GADD153 to promote androgen receptor degradation and decreases xenograft tumor growth
Categories:
Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Petiwala SM1, Berhe S1, Li G1, Puthenveetil AG1, Rahman O1, Nonn L2, Johnson JJ 
In:
PLoS ONE (2014) 9(3): e89772 
Zyflamend, a polyherbal mixture, down regulates class I and class II histone deacetylases and increases p21 levels in castrate-resistant prostate cancer cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Huang EC, Zhao Y, Chen G, Baek SJ, McEntee MF, Minkin S, Biggerstaff JP, Whelan J1. 
In:
BMC Complemen Altern Med (2014) 14:68: 1472 
Effects of sulforaphane and 3,3\\\'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Wong CP1, Hsu A1, Buchanan A2, Palomera-Sanchez Z1, Beaver LM1, Houseman EA2, Williams DE3, Dashwood RH3, Ho E4 
In:
PLoS ONE (2014) 9(1): e86787 
Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Bijnsdorp IV1, Geldof AA1, Lavaei M2, Piersma SR2, van Moorselaar RJ1, Jimenez CR 
In:
Other (2013) 23(2): 22097 
Selective modulation of endoplasmic reticulum stress markers in prostate cancer cells by a standardized mangosteen fruit extract
Categories:
Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Li G1, Petiwala SM1, Pierce DR1, Nonn L2, Johnson JJ3. 
In:
PLoS ONE (2013) 8(12): e81572 
Prostate-associated gene 4 (PAGE4) protects cells against stress by elevating p21 and suppressing reactive oxygen species production
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Yu Zeng1,3, Dong Gao1, John J Kim1,5, Takumi Shiraishi1, Naoki Terada1, Yoshiyuki Kakehi4, Chuize Kong3, Robert H Getzenberg1, Prakash Kulkarni1,2 
In:
Other (2013) 1(1): 39-52 
Zinc Finger 280B regulates sGCa1 and p53 in prostate cancer cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Gao S1, Hsieh CL, Zhou J, Shemshedini L 
In:
PLoS ONE (2013) 8(11): e78766 
ZFP91-A Newly Described Gene Potentially Involved in Prostate Pathology
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Paschke L1, Rucinski M, Ziolkowska A, Zemleduch T, Malendowicz W, Kwias Z, Malendowicz LK 
In:
Other (2013) 20: 453-59 
Reversal of chemosensitivity and induction of cell malignancy of a non-malignant prostate cancer cell line upon extracellular vesicle exposure
Categories:
Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Panagopoulos K1, Cross-Knorr S, Dillard C, Pantazatos D, Del Tatto M, Mills D, Goldstein L, Renzulli J, Quesenberry P, Chatterjee D 
In:
Mol Cancer (2013) 12(10): 118 
Loss of let-7 microRNA upregulates IL-6 in bone marrow-derived mesenchymal stem cells triggering a reactive stromal response to prostate cancer.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Sung SY1, Liao CH, Wu HP, Hsiao WC, Wu IH, Jinpu, Yu, Lin SH, Hsieh CL. 
In:
PLoS ONE (2013) 8(8): 71637 
Proteolytic cleavage and truncation of NDRG1 in human prostate cancer cells, but not normal prostate epithelial cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Ghalayini MK, Dong Q, Richardson DR, Assinder SJ. 
In:
Biosci Rep (2013) 33(3): 00042 
Betulinic acid selectively increases protein degradation and enhances prostate cancer-specific apoptosis: possible role for inhibition of deubiquitinase activity.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Reiner T, Parrondo R, de Las Pozas A, Palenzuela D, Perez-Stable C. 
In:
PLoS ONE (2013) 8(2): 56234 
Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCe without inhibiting Akt
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Sarveswaran S1, Gautam SC, Ghosh J. 
In:
Int J Oncol. (2012) 41(6): 2191-9 
Phenethyl isothiocyanate suppresses inhibitor of apoptosis family protein expression in prostate cancer cells in culture and in vivo.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Sakao K, Desineni S, Hahm ER, Singh SV. 
In:
Prostate (2012) 72(10): 1104-16 
Nicotinamide phosphoribosyl transferase (Nampt) is required for de novo lipogenesis in tumor cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Bowlby SC, Thomas MJ, D\'Agostino RB Jr, Kridel SJ. 
In:
PLoS ONE (2012) 7(6): 40195 
Regulation of prostate cancer cell invasion by modulation of extra- and intracellular redox balance.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Chaiswing L, Zhong W, Liang Y, Jones DP, Oberley TD. 
In:
Free Radic Biol Med (2012) 52(2): 452-61 
Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Cook CC, Kim A, Terao S, Gotoh A, Higuchi M. 
In:
Cell Death Differ (2012) 3: 258 
Cellular traction stresses increase with increasing metastatic potential.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Kraning-Rush CM, Califano JP, Reinhart-King CA. 
In:
PLoS ONE (2012) 7(2): 32572 
Flavonoid ampelopsin inhibits the growth and metastasis of prostate cancer in vitro and in mice.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Ni F, Gong Y, Li L, Abdolmaleky HM, Zhou JR. 
In:
PLoS ONE (2012) 7(6): 38802 
Silencing of DLC1 upregulates PAI-1 expression and reduces migration in normal prostate cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Shih YP, Takada Y, Lo SH. 
In:
Mol Cancer Res (2012) 10(1): 34-9 
Bioactive tanshinones in Salvia miltiorrhiza inhibit the growth of prostate cancer cells in vitro and in mice.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Gong Y, Li Y, Lu Y, Li L, Abdolmaleky H, Blackburn GL, Zhou JR. 
In:
Int J Cancer (2011) 129(5): 1042-52 
Coordinated regulation of polycomb group complexes through microRNAs in cancer.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Cao Q, Mani RS, Ateeq B, Dhanasekaran SM, Asangani IA, Prensner JR, Kim JH, Brenner JC, Jing X, Cao X, Wang R, Li Y, Dahiya A, Wang L, Pandhi M, Lonigro RJ, Wu YM, Tomlins SA, Palanisamy N, Qin Z, Yu J, Maher CA, Varambally S, Chinnaiyan AM. 
In:
Cancer Cell (2011) 20(2): 187-99 
Dimeric naphthoquinones, a novel class of compounds with prostate cancer cytotoxicity.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Ross AE, Emadi A, Marchionni L, Hurley PJ, Simons BW, Schaeffer EM, Vuica-Ross M. 
In:
BJU Int. (2011) 108(3): 447-54 
Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Clarke JD, Hsu A, Yu Z, Dashwood RH, Ho E. 
In:
Mol Nutr Food Res (2011) 55(7): 999-1009 
Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Kim JH, Dhanasekaran SM, Prensner JR, Cao X, Robinson D, Kalyana-Sundaram S, Huang C, Shankar S, Jing X, Iyer M, Hu M, Sam L, Grasso C, Maher CA, Palanisamy N, Mehra R, Kominsky HD, Siddiqui J, Yu J, Qin ZS, Chinnaiyan AM. 
In:
Genome Res (2011) 21(7): 1028-41 
Expression of nodal and nodal receptors in prostate stem cells and prostate cancer cells: autocrine effects on cell proliferation and migration.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Vo BT1, Khan SA. 
In:
Prostate (2011) 71(10): 1084-96 
Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Lin J, Haffner MC, Zhang Y, Lee BH, Brennen WN, Britton J, Kachhap SK, Shim JS, Liu JO, Nelson WG, Yegnasubramanian S, Carducci MA. 
In:
Prostate (2011) 71(4): 333-43 
High fat diet reduces the expression of glutathione peroxidase 3 in mouse prostate.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Sekine Y, Osei-Hwedieh D, Matsuda K, Raghavachari N, Liu D, Furuya Y, Koike H, Suzuki K, Remaley AT. 
In:
Prostate (2011) doi: 10: 1002 
Reactive oxygen species-dependent apoptosis by gugulipid extract of Ayurvedic medicine plant Commiphora mukul in human prostate cancer cells is regulated by c-Jun N-terminal kinase.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Xiao D1, Zeng Y, Prakash L, Badmaev V, Majeed M, Singh SV. 
In:
Mol Pharmacol (2011) 79(3): 499-507 
Distinct redox profiles of selected human prostate carcinoma cell lines: implications for rational design of redox therapy.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Chaiswing L, Zhong W, Oberley TD. 
In:
Cancers (2011) 3(3): 3557-3584 
TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Leshem O, Madar S, Kogan-Sakin I, Kamer I, Goldstein I, Brosh R, Cohen Y, Jacob-Hirsch J, Ehrlich M, Ben-Sasson S, Goldfinger N, Loewenthal R, Gazit E, Rotter V, Berger R. 
In:
PLoS ONE (2011) 6(7): 21650 
Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Place TL, Fitzgerald MP, Venkataraman S, Vorrink SU, Case AJ, Teoh ML, Domann FE. 
In:
PLoS ONE (2011) 6(1): 14617 
Repression of androgen receptor transcription through the E2F1/DNMT1 axis.
Categories:
 
Authors:
Valdez CD1, Davis JN, Odeh HM, Layfield TL, Cousineau CS, Berton TR, Johnson DG, Wojno KJ, Day ML. 
In:
PLoS ONE (2011) 6(9): 25187 
Defective molecular timer in the absence of nucleotides leads to inefficient caspase activation
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Zhang H1, Gogada R, Yadav N, Lella RK, Badeaux M, Ayres M, Gandhi V, Tang DG, Chandra D. 
In:
PLoS ONE (2011) 6(1): e16379 
Androgen-induced TMPRSS2:ERG fusion in nonmalignant prostate epithelial cells.
Categories:
Primary Cells and Media, Transfection 
Authors:
Bastus NC, Boyd LK, Mao X, Stankiewicz E, Kudahetti SC, Oliver RT, Berney DM, Lu YJ. 
In:
Cancer Res (2010) 70(23): 9544-9548 
Thioredoxin 1 as a subcellular biomarker of redox imbalance in human prostate cancer progression.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media, Transfection 
Authors:
Shan W, Zhong W, Zhao R, Oberley TD. 
In:
Free Radic Biol Med (2010) 49(12): 2078-87 
MiRNA 26a expression in a novel panel of African American prostate cancer cell lines.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Theodore SC1, Rhim JS, Turner T, Yates C. 
In:
Other (2010) 20(1 Suppl 1: 96-100 
Id1 overexpression is independent of repression and epigenetic silencing of tumor suppressor genes in melanoma.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Healey MA, Deaton SL, Alder JK, Winnepenninckx V, Casero RA Jr, Herman JG. 
In:
Epigenetics (2010) 5(5): 410-21 
Transcriptional regulation of Rex1 (zfp42) in normal prostate epithelial cells and prostate cancer cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Lee MY, Lu A, Gudas LJ. 
In:
J Cell Physiol (2010) 224(1): 17-27 
Differential regulation of steroid nuclear receptor coregulator expression between normal and neoplastic prostate epithelial cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Heemers HV, Schmidt LJ, Kidd E, Raclaw KA, Regan KM, Tindall DJ. 
In:
Prostate (2010) 70(9): 959-70 
Mutant p53 initiates a feedback loop that involves Egr-1/EGF receptor/ERK in prostate cancer cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Sauer L, Gitenay D, Vo C, Baron VT. 
In:
Oncogene (2010) 29(18): 2628-37 
A NADPH oxidase-dependent redox signaling pathway mediates the selective radiosensitization effect of parthenolide in prostate cancer cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Sun Y1, St Clair DK, Xu Y, Crooks PA, St Clair WH. 
In:
Cancer Res (2010) 70(7): 2880-90 
Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Romero D, Terzic A, Conley BA, Craft CS, Jovanovic B, Bergan RC, Vary CP 
In:
Carcinogenesis (2010) 31(3): 359-66 
Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Murakami M, Ugai H, Belousova N, Pereboev A, Dent P, Fisher PB, Everts M, Curiel DT. 
In:
Prostate (2010) 70(4): 362-76 
Cholesterol homeostasis in two commonly used human prostate cancer cell-lines, LNCaP and PC-3.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Krycer JR, Kristiana I, Brown AJ. 
In:
PLoS ONE (2009) 4(12): 8496 
Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Lin C, Yang L, Tanasa B, Hutt K, Ju BG, Ohgi K, Zhang J, Rose DW, Fu XD, Glass CK, Rosenfeld MG. 
In:
Cell (2009) 139(6): 1069-83 
Synthetic mRNA splicing modulator compounds with in vivo antitumor activity.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Lagisetti C, Pourpak A, Goronga T, Jiang Q, Cui X, Hyle J, Lahti JM, Morris SW, Webb TR. 
In:
J Med Chem (2009) 52(22): 6979-90 
Uptake of resveratrol and role of resveratrol-targeting protein, quinone reductase 2, in normally cultured human prostate cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Hsieh TC. 
In:
Asian J Androl (2009) 11(6): 653-61 
alpha-Tocopheryl succinate and derivatives mediate the transcriptional repression of androgen receptor in prostate cancer cells by targeting the PP2A-JNK-Sp1-signaling axis.
Categories:
Primary Cells and Media 
Authors:
Huang PH, Wang D, Chuang HC, Wei S, Kulp SK, Chen CS. 
In:
Carcinogenesis (2009) 30(7): 1125-31 
Fibrils of prostatic acid phosphatase fragments boost infections with XMRV (xenotropic murine leukemia virus-related virus), a human retrovirus associated with prostate cancer.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Hong S, Klein EA, Das Gupta J, Hanke K, Weight CJ, Nguyen C, Gaughan C, Kim KA, Bannert N, Kirchhoff F, Munch J, Silverman RH. 
In:
J Virol (2009) 83(14): 6995-7003 
A truncated T antigen expressed from an alternatively spliced BK virus early mRNA.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Abend JR, Joseph AE, Das D, Campbell-Cecen DB, Imperiale MJ. 
In:
J Gen Virol (2009) 90(Pt 5): 1238-45 
Keratinocyte-derived chemokine induces prostate epithelial hyperplasia and reactive stroma in a novel transgenic mouse model.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Schauer IG, Ressler SJ, Rowley DR. 
In:
Prostate (2009) 69(4): 373-84 
Androgen-independent prostate cancer cells acquire the complete steroidogenic potential of synthesizing testosterone from cholesterol.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Dillard PR, Lin MF, Khan SA. 
In:
Mol Endocrinol (2008) 295(1-2): 115-20 
Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Floryk D, Thompson TC. 
In:
Int J Cancer (2008) 123(10): 2294-302 
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