NO - the lysis reagent in the MycoAlert® Assay is not strong enough to lyse bacteria / yeast.

Also, the enzymes utilized are not very common in bacteria or yeast – but are universal among the mollicute family. Bacterial contamination is characterized by rapid appearance of turbidity in cell culture media. One of the dangers of mycoplasma infection is that they do not produce turbidity, hence the need for a test such as the MycoAlert® Assay.