Q:

Can I replace the RAFT collagen with another hydrogel type ex. Matrigel?

A:

Complete substitution for collagen type I within the RAFT system (including its absorption step) is not possible, but one can certainly add Matrigel or laminins to the RAFT collagen mixture, up to a certain ratio. The absorption conditions (ex. time) might need to be adjusted.

Categories:
3D Cell Culture
Research Areas:
Regenerative medicine