Osteoblast, (NHOst) human

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Osteoblasts produce bone matrix and prime it for mineralization.  Human osteoblasts are sourced from spongy bone tissue.

Cell Type:
Bone
Tissue Origin:
bone
Species:
human
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Research Area:
Cancer Research/Cell Biology
Dermatology/Tissue Engineering
Cell Characteristics:
Adherent

Recommended Media

Osteoblast Growth Medium

Clonetics™ OGM™ is specially formulated for the growth and expansion of human osteoblasts.
Contains 10% FBS

CC-4194 - OGM Differentiation SingleQuots - induce osteoblast differentiation and mineralization

Transfection Information

In case no data are shown for the selected cell type, please take a look at our optimization strategy or contact our Scientific Support Teams to get further guidance on how to easily determine optimal Nucleofection conditions yourself.

Citations (18)

Bioactive nanocomposite PLDL/nano-hydroxyapatite electrospun membranes for bone tissue engineering
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media, Bioassay  
Authors:
Rajzer I1, Menaszek E, Kwiatkowski R, Chrzanowski W 
In:
Other (2014) 25(5): 1239-47 
Mechanisms of palmitate-induced cell death in human osteoblasts.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Gunaratnam K1, Vidal C, Boadle R, Thekkedam C, Duque G 
In:
Other (2013) 2(12): 1382-9 
Preliminary results of implantation in animal model and osteoblast culture evaluation of prototypes of biomimetic multispiked connecting scaffold for noncemented stemless resurfacing hip arthroplasty endoprostheses
Categories:
Primary Cells and Media 
Authors:
Uklejewski R, Rogala P, Winiecki M, Kedzia A, Ruszkowski P 
In:
Biomed Res Int. (2013) 2013: 689089 
Pharmacological targeting of the PI3K/mTOR pathway alters the release of angioregulatory mediators both from primary human acute myeloid leukemia cells and their neighboring stromal cells
Categories:
Primary Cells and Media 
Authors:
Reikvam H, Nepstad I, Bruserud Ø, Hatfield KJ 
In:
OncoTarget (2013) 4(6): 830-43 
A diarylheptanoid phytoestrogen from Curcuma comosa, 1,7-diphenyl-4,6-heptadien-3-ol, accelerates human osteoblast proliferation and differentiation.
Categories:
Primary Cells and Media 
Authors:
Tantikanlayaporn D1, Robinson LJ, Suksamrarn A, Piyachaturawat P, Blair HC 
In:
Other (2013) 20(8-9): 676-82 
Characterization of adipose-derived mesenchymal stem cell combinations for vascularized bone engineering
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Valenzuela CD, Allori AC, Reformat DD, Sailon AM, Allen RJ Jr, Davidson EH, Alikhani M, Bromage TG, Ricci JL, Warren SM 
In:
Tissue Eng (2013) 19(11-12): 1373-85 
Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Fu W, Sharma SS, Ma L, Chu B, Bui MM, Reed D, Pledger WJ 
In:
Cell Death Dis. (2013) 4: e566 
Dkk-3, a secreted wnt antagonist, suppresses tumorigenic potential and pulmonary metastasis in osteosarcoma
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Lin CH, Guo Y, Ghaffar S, McQueen P, Pourmorady J, Christ A, Rooney K, Ji T, Eskander R, Zi X, Hoang BH 
In:
Sarcoma (2013) 2013: 147541 
Differentiation of human mesenchymal stem cells on niobium-doped fluorapatite glass-ceramics
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Kushwaha M, Pan X, Holloway JA, Denry IL 
In:
Dental Materials (2012) 28(3): 252-260 
Global gene expression analysis of the interaction between cancer cells and osteoblasts to predict bone metastasis in breast cancer
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Rajski M, Vogel B, Baty F, Rochlitz C, Buess M 
In:
PLoS ONE (2012) 7(1): e29743 
MicroRNA-199a-3p is downregulated in human osteosarcoma and regulates cell proliferation and migration
Categories:
Primary Cells and Media 
Authors:
Duan Z, Choy E, Harmon D, Liu X, Susa M, Mankin H, Hornicek F. 
In:
Mol Cancer Ther (2011) 10(8): 1337-45 
Inhibition of fatty acid biosynthesis prevents adipocyte lipotoxicity on human osteoblasts in vitro
Categories:
Primary Cells and Media 
Authors:
Elbaz A, Wu X, Rivas D, Gimble JM, Duque G. 
In:
J Cell Mol Med (2010) 14(4): 982-91 
The kinase Mirk is a potential therapeutic target in osteosarcoma
Categories:
Primary Cells and Media 
Authors:
Yang C1, Ji D, Weinstein EJ, Choy E, Hornicek FJ, Wood KB, Liu X, Mankin H, Duan Z. 
In:
Carcinogenesis (2010) 31(4): 552-8 
Wnt inhibitory factor 1 decreases tumorigenesis and metastasis in osteosarcoma
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Rubin EM, Guo Y, Tu K, Xie J, Zi X, Hoang BH. 
In:
Mol Cancer Ther (2010) 9(3): 731-41 
Endodontic antimicrobial photodynamic therapy: safety assessment in mammalian cell cultures
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Xu Y1, Young MJ, Battaglino RA, Morse LR, Fontana CR, Pagonis TC, Kent R, Soukos NS 
In:
Journal of Endodontics (2009) 35(11): 1567-72 
Effect of lamin A/C knockdown on osteoblast differentiation and function
Categories:
Primary Cells and Media 
Authors:
Akter R, Rivas D, Geneau G, Drissi H, Duque G. 
In:
J Bone Joint Surg Am (2009) 24(2): 283-93 
A soluble activin type IIA receptor induces bone formation and improves skeletal integrity
Categories:
Primary Cells and Media 
Authors:
Pearsall RS, Canalis E, Cornwall-Brady M, Underwood KW, Haigis B, Ucran J, Kumar R, Pobre E, Grinberg A, Werner ED, Glatt V, Stadmeyer L, Smith D, Seehra J, Bouxsein ML. 
In:
Proc Natl Acad Sci USA (2008) 105(19): 7082-7 
CX3CR1 is expressed by prostate epithelial cells and androgens regulate the levels of CX3CL1/fractalkine in the bone marrow: potential role in prostate cancer bone tropism.
Categories:
Primary Cells and Media, Classical Media and Reagents, Serum-free and Speciality Media 
Authors:
Jamieson WL, Shimizu S, D\'Ambrosio JA, Meucci O, Fatatis A 
In:
Cancer Res (2008) 68(6): 1715-22 
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